Patients on HU vs not on HU
| . | HU (n = 60) . | No HU (n = 40) . | P . |
|---|---|---|---|
| Genotype | |||
| HbSS | 59 (98%) | 36 (90%) | .15 |
| HbSβ0 | 1 (2%) | 4 (10%) | .28 |
| Age, y | 11 ± 3.7 | 12 ± 2.3 | .57 |
| Hb, g/dL | 9.43 ± 1.30 | 8.60 ± 2.40 | .03 |
| MCV, fL | 92.10 ± 12.10 | 82.50 ± 21.20 | .003 |
| Platelet count, K/µL | 367 ± 134 | 317 ± 145 | .08 |
| HbF, % | 9.70 ± 8.60 | 5.20 ± 7.40 | .008 |
| LVEDd z-score | 1.85 ± 1.20 | 1.85 ± 1.10 | 1.00 |
| LVESd z-score | 1.06 ± 1.27 | 1.03 ± 1.17 | 1.00 |
| LV volume z-score | 2.10 ± 1.40 | 1.92 ± 1.40 | .53 |
| LV mass z-score | 0.82 ± 1.50 | 0.93 ± 1.62 | .73 |
| LV mass index, g/ht2.7 | 42 ± 10 | 42 ± 10 | 1.00 |
| LVSF, % | 37 ± 4 | 37 ± 4 | .69 |
| LVEF, % | 61 ± 5 | 62 ± 5 | .26 |
| TR, m/s | 2.30 ± 0.20 | 2.40 ± 0.30 | .95 |
| . | HU (n = 60) . | No HU (n = 40) . | P . |
|---|---|---|---|
| Genotype | |||
| HbSS | 59 (98%) | 36 (90%) | .15 |
| HbSβ0 | 1 (2%) | 4 (10%) | .28 |
| Age, y | 11 ± 3.7 | 12 ± 2.3 | .57 |
| Hb, g/dL | 9.43 ± 1.30 | 8.60 ± 2.40 | .03 |
| MCV, fL | 92.10 ± 12.10 | 82.50 ± 21.20 | .003 |
| Platelet count, K/µL | 367 ± 134 | 317 ± 145 | .08 |
| HbF, % | 9.70 ± 8.60 | 5.20 ± 7.40 | .008 |
| LVEDd z-score | 1.85 ± 1.20 | 1.85 ± 1.10 | 1.00 |
| LVESd z-score | 1.06 ± 1.27 | 1.03 ± 1.17 | 1.00 |
| LV volume z-score | 2.10 ± 1.40 | 1.92 ± 1.40 | .53 |
| LV mass z-score | 0.82 ± 1.50 | 0.93 ± 1.62 | .73 |
| LV mass index, g/ht2.7 | 42 ± 10 | 42 ± 10 | 1.00 |
| LVSF, % | 37 ± 4 | 37 ± 4 | .69 |
| LVEF, % | 61 ± 5 | 62 ± 5 | .26 |
| TR, m/s | 2.30 ± 0.20 | 2.40 ± 0.30 | .95 |
Data are expressed as mean ± standard deviation unless otherwise indicated. MCV, mean corpuscular volume.