Clinical characteristics of study population (N = 100)
| Characteristic . | Mean ± SD or N . | Range or % . |
|---|---|---|
| Age (y) | 12 ± 4.9 | 3 to 22 |
| Male sex | 58 | 58 |
| Genotype | ||
| HbSS | 95 | 95 |
| HbSβ0 | 5 | 5 |
| On HU | 60 | 60 |
| Hb (g/dL) | 9.28 ± 1.20 | 5.40 to 13 |
| MCV (fL) | 86 ± 11 | 61 to 117 |
| Platelet count (K/µL) | 365 ± 130 | 110 to 695 |
| HbF (%) | 8.10 ± 8.40 | 1 to 32 |
| LVEDd z-score | 1.85 ± 1.27 | −1.83 to 4.47 |
| LVESd z-score | 1.06 ± 1.19 | −1.2 to 3.43 |
| LV volume z-score | 2.03 ± 1.44 | −1.80 to 5.70 |
| LV mass z-score | 0.87 ± 1.55 | −2.50 to 5.90 |
| LV mass index (g/ht2.7) | 42.1 ± 10.64 | 17 to 69.80 |
| Dilated left ventricle | 50 | 50 |
| LVSF (%) | 37 ± 17 | 26 to 48 |
| <28% | 3 | 3 |
| LVEF (%) | 62 ± 29 | 45 to 75 |
| <55% | 4 | 4 |
| TR (m/s) | 2.30 ± 0.20 | 1.70-2.80 |
| ≥2.5 m/s | 32 | 32 |
| Characteristic . | Mean ± SD or N . | Range or % . |
|---|---|---|
| Age (y) | 12 ± 4.9 | 3 to 22 |
| Male sex | 58 | 58 |
| Genotype | ||
| HbSS | 95 | 95 |
| HbSβ0 | 5 | 5 |
| On HU | 60 | 60 |
| Hb (g/dL) | 9.28 ± 1.20 | 5.40 to 13 |
| MCV (fL) | 86 ± 11 | 61 to 117 |
| Platelet count (K/µL) | 365 ± 130 | 110 to 695 |
| HbF (%) | 8.10 ± 8.40 | 1 to 32 |
| LVEDd z-score | 1.85 ± 1.27 | −1.83 to 4.47 |
| LVESd z-score | 1.06 ± 1.19 | −1.2 to 3.43 |
| LV volume z-score | 2.03 ± 1.44 | −1.80 to 5.70 |
| LV mass z-score | 0.87 ± 1.55 | −2.50 to 5.90 |
| LV mass index (g/ht2.7) | 42.1 ± 10.64 | 17 to 69.80 |
| Dilated left ventricle | 50 | 50 |
| LVSF (%) | 37 ± 17 | 26 to 48 |
| <28% | 3 | 3 |
| LVEF (%) | 62 ± 29 | 45 to 75 |
| <55% | 4 | 4 |
| TR (m/s) | 2.30 ± 0.20 | 1.70-2.80 |
| ≥2.5 m/s | 32 | 32 |
MCV, mean corpuscular volume; SD, standard deviation.