Table 2.

Relationship between IgG anti-B2GPI positivity and APS thrombotic clinical manifestations

First author (y)No. of participantsNo. of anti-B2GPI (+)Anti-B2GPI positivity cutoffNo. controls for assay calibrationLength of follow-upThrombosis
Forastiero (2005) 194 patients with persistently positive LA or aCL 64 IgG (+)
59 IgM (+) 
99th percentile 95 Median of 45 mo Increased risk 
Wahl (1998) 71 inpatients admitted for acute VTE 7 IgG (+) 3 SD from mean 20 Mean 4.9 y Increased risk 
First author (y)No. of participantsNo. of anti-B2GPI (+)Anti-B2GPI positivity cutoffNo. controls for assay calibrationLength of follow-upThrombosis
Forastiero (2005) 194 patients with persistently positive LA or aCL 64 IgG (+)
59 IgM (+) 
99th percentile 95 Median of 45 mo Increased risk 
Wahl (1998) 71 inpatients admitted for acute VTE 7 IgG (+) 3 SD from mean 20 Mean 4.9 y Increased risk 

SD, standard deviation.

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