Characteristics of index DVT and PTS scores according to group
| . | CVC-related thrombosis (n = 275) . | Non–CVC-related thrombosis (n = 38) . | P . |
|---|---|---|---|
| Extremity | .10* | ||
| Upper | 137 (50) | 13 (34) | |
| Lower | 138 (50) | 25 (66) | |
| Left side | .02* | ||
| Upper | 41 (30) | 6 (46) | |
| Lower | 53 (38) | 16 (64) | |
| No. of segments affected | 2 (1-2) | 3 (2-5) | <.001 |
| ≥1 completely occlusive segments at diagnosis | .03* | ||
| Upper | 76 (55) | 11 (95) | |
| Lower | 110 (80) | 23 (92) | |
| Edema in extremity | .004* | ||
| Upper | 41 (30) | 8 (63) | |
| Lower | 83 (60) | 21 (84) | |
| Pain in the extremity, n (%) | <.001* | ||
| Upper | 7 (5) | 6 (46) | |
| Lower | 6 (4) | 18 (72) | |
| Changes in skin color, temperature, or perfusion | .09* | ||
| Upper | 13 (9) | 0 (0) | |
| Lower | 41 (30) | 3 (12) | |
| Time from clinical suspicion or symptoms to DVT diagnosis, d | <.001* | ||
| Upper | 0 (0-0) | 0 (0-1) | |
| Lower | 0 (0-1) | 3 (2-6) | |
| CVC dysfunction | — | ||
| Upper | 13 (9) | — | |
| Lower | 3 (2) | — | |
| Treatment | <.001 | ||
| None | 43 (16) | 2 (5) | |
| Anticoagulation only | 232 (84) | 20 (53) | |
| Anticoagulation plus thrombolysis | 0 (0) | 16 (42) | |
| Length of treatment, mo | 3 (3-3) | 12 (3-26) | <.001 |
| No. of days on therapeutic anticoagulation in first month post-DVT | 27 (19-29) | 28 (27-29) | .03 |
| BMI percentile at time of PTS assessment | <.001 | ||
| Upper | 52.9 (17.5-80.4) | 80.5 (57.1-91.0) | |
| Lower | 52.1 (17.9-83.9) | 76.5 (63.2-96.9) | |
| CAPTSure score | .002* | ||
| Upper | 0.0 (0.0-9.1) | 13.0 (5.2-29.3) | |
| Lower | 3.6 (0.0-13.2) | 10.1 (3.8-32.0) | |
| Complete DVT resolution at 3 mo | 42 (17) | 7 (21) | .65 |
| Time of DVT resolution assessment, d | 88 (48-94) | 90 (30-95) | .99 |
| DVT recurrence in same DVT-affected extremity | 6 (2) | 3 (8) | .03 |
| Time to recurrence, d | 617 (390-903) | 94 (68-522) | .19 |
| . | CVC-related thrombosis (n = 275) . | Non–CVC-related thrombosis (n = 38) . | P . |
|---|---|---|---|
| Extremity | .10* | ||
| Upper | 137 (50) | 13 (34) | |
| Lower | 138 (50) | 25 (66) | |
| Left side | .02* | ||
| Upper | 41 (30) | 6 (46) | |
| Lower | 53 (38) | 16 (64) | |
| No. of segments affected | 2 (1-2) | 3 (2-5) | <.001 |
| ≥1 completely occlusive segments at diagnosis | .03* | ||
| Upper | 76 (55) | 11 (95) | |
| Lower | 110 (80) | 23 (92) | |
| Edema in extremity | .004* | ||
| Upper | 41 (30) | 8 (63) | |
| Lower | 83 (60) | 21 (84) | |
| Pain in the extremity, n (%) | <.001* | ||
| Upper | 7 (5) | 6 (46) | |
| Lower | 6 (4) | 18 (72) | |
| Changes in skin color, temperature, or perfusion | .09* | ||
| Upper | 13 (9) | 0 (0) | |
| Lower | 41 (30) | 3 (12) | |
| Time from clinical suspicion or symptoms to DVT diagnosis, d | <.001* | ||
| Upper | 0 (0-0) | 0 (0-1) | |
| Lower | 0 (0-1) | 3 (2-6) | |
| CVC dysfunction | — | ||
| Upper | 13 (9) | — | |
| Lower | 3 (2) | — | |
| Treatment | <.001 | ||
| None | 43 (16) | 2 (5) | |
| Anticoagulation only | 232 (84) | 20 (53) | |
| Anticoagulation plus thrombolysis | 0 (0) | 16 (42) | |
| Length of treatment, mo | 3 (3-3) | 12 (3-26) | <.001 |
| No. of days on therapeutic anticoagulation in first month post-DVT | 27 (19-29) | 28 (27-29) | .03 |
| BMI percentile at time of PTS assessment | <.001 | ||
| Upper | 52.9 (17.5-80.4) | 80.5 (57.1-91.0) | |
| Lower | 52.1 (17.9-83.9) | 76.5 (63.2-96.9) | |
| CAPTSure score | .002* | ||
| Upper | 0.0 (0.0-9.1) | 13.0 (5.2-29.3) | |
| Lower | 3.6 (0.0-13.2) | 10.1 (3.8-32.0) | |
| Complete DVT resolution at 3 mo | 42 (17) | 7 (21) | .65 |
| Time of DVT resolution assessment, d | 88 (48-94) | 90 (30-95) | .99 |
| DVT recurrence in same DVT-affected extremity | 6 (2) | 3 (8) | .03 |
| Time to recurrence, d | 617 (390-903) | 94 (68-522) | .19 |
Data are presented as median (25th-75th percentile) or n (%).
P value for CVC yes/no variable (see Table 3 for more details).