Table 1.

Dose adjustment of eltrombopag

Platelet countDose adjustment or response
<50 × 109/L after treatment for at least 2 weeks Increase the daily dose by to a maximum of 75 mg/day. 
>150 × 109/L at 2-week intervals Decrease the daily dose by 12.5 mg/day. 
>250 × 109/L Treatment was interrupted and resumed at next lowest dose based on 12.5-mg increments once the platelet count had decreased to <100 × 109/L. 
Platelet countDose adjustment or response
<50 × 109/L after treatment for at least 2 weeks Increase the daily dose by to a maximum of 75 mg/day. 
>150 × 109/L at 2-week intervals Decrease the daily dose by 12.5 mg/day. 
>250 × 109/L Treatment was interrupted and resumed at next lowest dose based on 12.5-mg increments once the platelet count had decreased to <100 × 109/L. 
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