Dose adjustment of eltrombopag
Platelet count . | Dose adjustment or response . |
---|---|
<50 × 109/L after treatment for at least 2 weeks | Increase the daily dose by to a maximum of 75 mg/day. |
>150 × 109/L at 2-week intervals | Decrease the daily dose by 12.5 mg/day. |
>250 × 109/L | Treatment was interrupted and resumed at next lowest dose based on 12.5-mg increments once the platelet count had decreased to <100 × 109/L. |
Platelet count . | Dose adjustment or response . |
---|---|
<50 × 109/L after treatment for at least 2 weeks | Increase the daily dose by to a maximum of 75 mg/day. |
>150 × 109/L at 2-week intervals | Decrease the daily dose by 12.5 mg/day. |
>250 × 109/L | Treatment was interrupted and resumed at next lowest dose based on 12.5-mg increments once the platelet count had decreased to <100 × 109/L. |