Patient characteristics
Characteristic . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . |
---|---|---|---|---|
Age, y | 72 | 71 | 66 | 64 |
Sex | Male | Female | Male | Female |
Preexisting conditions and past medical history | Radioiodine-treated autoimmune thyroiditis | Latent hyperthyroidism, nodular goiter, breast cancer, stroke | Hypertension, mild thrombocytopenia | Hypertension, chronic obstructive pulmonary disease, steatosis hepatis |
Allergies | Pollen | None | None | None |
Medication on admission | None | Aspirin, metamizole, denosumab (once every 6 mo) | Amlodipine, valsartan, hydrochlorothiazide, tamsulosin | Candesartan, hydrochlorothiazide, zolpidem, salbutamol, tilidine, tiotropium bromide |
Time from vaccination to admission, days | 11 | 11 | 2 | 15 |
Symptoms | Petechiae, epistaxis, headache | Petechiae, hyposphagma | Petechiae | None |
Platelet count nadir × 109/L | <5 | <5 | <5 | 6 |
D-dimer peak, mg/L (reference range, 0.21-0.52 mg/L FEU) | 0.83 | 1.16 | 0.35 | 0.51 |
PF4-polyanion antibodies (ELISA) | Negative | Negative | Negative | Negative |
Treatment | Intravenous immunoglobulin, glucocorticoids | Intravenous immunoglobulin, glucocorticoids, thrombopoietin receptor agonist | Glucocorticoids | Glucocorticoids |
Characteristic . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . |
---|---|---|---|---|
Age, y | 72 | 71 | 66 | 64 |
Sex | Male | Female | Male | Female |
Preexisting conditions and past medical history | Radioiodine-treated autoimmune thyroiditis | Latent hyperthyroidism, nodular goiter, breast cancer, stroke | Hypertension, mild thrombocytopenia | Hypertension, chronic obstructive pulmonary disease, steatosis hepatis |
Allergies | Pollen | None | None | None |
Medication on admission | None | Aspirin, metamizole, denosumab (once every 6 mo) | Amlodipine, valsartan, hydrochlorothiazide, tamsulosin | Candesartan, hydrochlorothiazide, zolpidem, salbutamol, tilidine, tiotropium bromide |
Time from vaccination to admission, days | 11 | 11 | 2 | 15 |
Symptoms | Petechiae, epistaxis, headache | Petechiae, hyposphagma | Petechiae | None |
Platelet count nadir × 109/L | <5 | <5 | <5 | 6 |
D-dimer peak, mg/L (reference range, 0.21-0.52 mg/L FEU) | 0.83 | 1.16 | 0.35 | 0.51 |
PF4-polyanion antibodies (ELISA) | Negative | Negative | Negative | Negative |
Treatment | Intravenous immunoglobulin, glucocorticoids | Intravenous immunoglobulin, glucocorticoids, thrombopoietin receptor agonist | Glucocorticoids | Glucocorticoids |
ELISA, enzyme-linked immunosorbent assay; FEU, fibrinogen equivalent units.