Table 1.

Patient characteristics

CharacteristicPatient 1Patient 2Patient 3Patient 4
Age, y 72 71 66 64 
Sex Male Female Male Female 
Preexisting conditions and past medical history Radioiodine-treated autoimmune thyroiditis Latent hyperthyroidism, nodular goiter, breast cancer, stroke Hypertension, mild thrombocytopenia Hypertension, chronic obstructive pulmonary disease, steatosis hepatis 
Allergies Pollen None None None 
Medication on admission None Aspirin, metamizole, denosumab (once every 6 mo) Amlodipine, valsartan, hydrochlorothiazide, tamsulosin Candesartan, hydrochlorothiazide, zolpidem, salbutamol, tilidine, tiotropium bromide 
Time from vaccination to admission, days 11 11 15 
Symptoms Petechiae, epistaxis, headache Petechiae, hyposphagma Petechiae None 
Platelet count nadir × 109/L <5 <5 <5 
D-dimer peak, mg/L (reference range, 0.21-0.52 mg/L FEU) 0.83 1.16 0.35 0.51 
PF4-polyanion antibodies (ELISA) Negative Negative Negative Negative 
Treatment Intravenous immunoglobulin, glucocorticoids Intravenous immunoglobulin, glucocorticoids, thrombopoietin receptor agonist Glucocorticoids Glucocorticoids 
CharacteristicPatient 1Patient 2Patient 3Patient 4
Age, y 72 71 66 64 
Sex Male Female Male Female 
Preexisting conditions and past medical history Radioiodine-treated autoimmune thyroiditis Latent hyperthyroidism, nodular goiter, breast cancer, stroke Hypertension, mild thrombocytopenia Hypertension, chronic obstructive pulmonary disease, steatosis hepatis 
Allergies Pollen None None None 
Medication on admission None Aspirin, metamizole, denosumab (once every 6 mo) Amlodipine, valsartan, hydrochlorothiazide, tamsulosin Candesartan, hydrochlorothiazide, zolpidem, salbutamol, tilidine, tiotropium bromide 
Time from vaccination to admission, days 11 11 15 
Symptoms Petechiae, epistaxis, headache Petechiae, hyposphagma Petechiae None 
Platelet count nadir × 109/L <5 <5 <5 
D-dimer peak, mg/L (reference range, 0.21-0.52 mg/L FEU) 0.83 1.16 0.35 0.51 
PF4-polyanion antibodies (ELISA) Negative Negative Negative Negative 
Treatment Intravenous immunoglobulin, glucocorticoids Intravenous immunoglobulin, glucocorticoids, thrombopoietin receptor agonist Glucocorticoids Glucocorticoids 

ELISA, enzyme-linked immunosorbent assay; FEU, fibrinogen equivalent units.

Close Modal

or Create an Account

Close Modal
Close Modal