Durability of benefit in deep responders: PFS and duration of response
. | Continuous Ven (n = 14) . | Limited-duration Ven* (n = 19) . | All deep responders (n = 33) . |
---|---|---|---|
Median time on Ven, y (range) | 5.6 (2.4-6.6) | 1.4 (0.4-4.2) | 3.1 (0.5-6.6) |
PFS† | |||
Median, y (95% CI) | 6.6 (4.6-6.6) | 6.5 (3.6-6.5) | 6.5 (5.5-6.6) |
3-y estimate (95% CI) | 92.9% (59.1-99.0) | 87.1% (57.3-96.6) | 89.9% (71.8-96.6) |
5-y estimate (95% CI) | 78.6% (47.2-92.5) | 79.8% (49.4-93.0) | 79.1% (59.1-90.0) |
Duration of response† | |||
Median, y (95% CI) | 6.3 (4.4-6.3) | 6.2 (3.4-6.2) | 6.2 (5.4-6.3) |
3-y estimate (95% CI) | 85.7% (53.9-96.2) | 86.7% (56.4-96.5) | 86.2% (67.2-94.6) |
5-y estimate (95% CI) | 70.7% (39.4-87.9) | 79.4% (48.8-92.9) | 73.9% (52.4-86.8) |
. | Continuous Ven (n = 14) . | Limited-duration Ven* (n = 19) . | All deep responders (n = 33) . |
---|---|---|---|
Median time on Ven, y (range) | 5.6 (2.4-6.6) | 1.4 (0.4-4.2) | 3.1 (0.5-6.6) |
PFS† | |||
Median, y (95% CI) | 6.6 (4.6-6.6) | 6.5 (3.6-6.5) | 6.5 (5.5-6.6) |
3-y estimate (95% CI) | 92.9% (59.1-99.0) | 87.1% (57.3-96.6) | 89.9% (71.8-96.6) |
5-y estimate (95% CI) | 78.6% (47.2-92.5) | 79.8% (49.4-93.0) | 79.1% (59.1-90.0) |
Duration of response† | |||
Median, y (95% CI) | 6.3 (4.4-6.3) | 6.2 (3.4-6.2) | 6.2 (5.4-6.3) |
3-y estimate (95% CI) | 85.7% (53.9-96.2) | 86.7% (56.4-96.5) | 86.2% (67.2-94.6) |
5-y estimate (95% CI) | 70.7% (39.4-87.9) | 79.4% (48.8-92.9) | 73.9% (52.4-86.8) |