Table 3.

Descriptive information and association between log2-EASIX-PRE and posttransplantation complications

Descriptive InformationAssociationP
% (95% CI)HR (95% CI)
Association between EASIX-PRE and posttransplantation outcomes    
 OS  1.19 (1.04-1.37) .011 
  1 y 63.1 (54.8-70.3)   
  2 y 55.4 (44.6-62.4)   
 NRM  1.28 (1.08-1.53) .004 
  1 y 26.6 (19.8-32.7)   
  2 y 28.7 (21.5-32.7)   
 PFS  1.102 (0.89-1.35) .360 
  1 y 56.0 (47.5-63.7)   
  2 y 51.8 (42.9-59.9)   
 CIR  1.12 (0.82-1.54) .450 
  1 y 18.9 (13.0-25.8)   
  2 y 22.9 (16.1-30.4)   
Association between EASIX-PRE and cumulative incidences    
 ICU admission*    
  Day +180 18.6 (13.1-24.9) 1.28 (1.08-1.53) .004 
 SOS*    
  Day +28 7.2 (3.9-11.8) 0.79 (0.42-1.46) .460 
 TAM*    
  Day +180 11.4 (7.1-16.7) 1.17 (0.90-1.51) .230 
 Graft failure    
  Day +180 1.2 (0.1-4.0) 1.01 (0.51-2.26) .841 
 GVHD    
  Grade II-IV acute GVHD at day +100 18.8 (13.2-25.1) 0.99 (0.82-1.18) .920 
  Grade III-IV acute GVHD at day +100 10.3 (6.2-15.5) 0.99 (0.79-1.25) .970 
  Moderate/severe chronic GVHD at 1 y 22.1 (15-1-29.9) 0.89 (0.72-1.11) .320 
Descriptive InformationAssociationP
% (95% CI)HR (95% CI)
Association between EASIX-PRE and posttransplantation outcomes    
 OS  1.19 (1.04-1.37) .011 
  1 y 63.1 (54.8-70.3)   
  2 y 55.4 (44.6-62.4)   
 NRM  1.28 (1.08-1.53) .004 
  1 y 26.6 (19.8-32.7)   
  2 y 28.7 (21.5-32.7)   
 PFS  1.102 (0.89-1.35) .360 
  1 y 56.0 (47.5-63.7)   
  2 y 51.8 (42.9-59.9)   
 CIR  1.12 (0.82-1.54) .450 
  1 y 18.9 (13.0-25.8)   
  2 y 22.9 (16.1-30.4)   
Association between EASIX-PRE and cumulative incidences    
 ICU admission*    
  Day +180 18.6 (13.1-24.9) 1.28 (1.08-1.53) .004 
 SOS*    
  Day +28 7.2 (3.9-11.8) 0.79 (0.42-1.46) .460 
 TAM*    
  Day +180 11.4 (7.1-16.7) 1.17 (0.90-1.51) .230 
 Graft failure    
  Day +180 1.2 (0.1-4.0) 1.01 (0.51-2.26) .841 
 GVHD    
  Grade II-IV acute GVHD at day +100 18.8 (13.2-25.1) 0.99 (0.82-1.18) .920 
  Grade III-IV acute GVHD at day +100 10.3 (6.2-15.5) 0.99 (0.79-1.25) .970 
  Moderate/severe chronic GVHD at 1 y 22.1 (15-1-29.9) 0.89 (0.72-1.11) .320 

CIR, cumulative incidence of relapse; PFS, progression-free survival.

*

Cumulative incidence analysis considering death as competing event.

Cumulative Incidence analysis considering death and relapse as competing events.

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