Table 2.

Hematologic parameters for Neo1fl/fl;Alb-Cre−, Neo1fl/wt;Alb-Cre+, and Neo1fl/fl;Alb-Cr+ female mice

Neo1fl/fl;Alb-Cre− (5 wk) (n = 4)Neo1fl/fl;Alb-Cre+ (5 wk) (n = 7)Neo1fl/fl;Alb-Cre− (8 wk) (n = 6)Neo1fllwt;Alb-Cre+ (8 wk) (n = 5)Neo1fl/fl;Alb-Cre+ (8 wk) (n = 8)Neo1fl/fl;Alb-Cre− (15 wk) (n = 4)Neo1fl/fl;Alb-Cre+ (15 wk) (n = 5)
RBC 8.57 ± 0.17 8.48 ± 0.25 8.83 ± 0.40 8.98 ± 0.33 8.83 ± 0.41 9.19 ± 0.51 9.15 ± 0.48 
Hb 12.65 ± 0.24 12.95 ± 0.15* 12.76 ± 0.51 12.90 ± 0.61 13.81 ± 0.36† 13.57 ± 0.35 13.90 ± 0.36 
HCT 42.72 ± 0.55 44.18 ± 0.81* 40.06 ± 1.49 40.86 ± 3.03 43.93 ± 1.47† 42.35 ± 2.26 44.60 ± 2.47 
MCV 48.40 ± 0.39 50.40 ± 1.66* 45.36 ± 1.16 45.86 ± 0.28 49.81 ± 1.64† 46.10 ± 1.48 48.70 ± 0.63* 
MCH 14.40 ± 0.28 14.85 ± 0.29* 14.45 ± 0.58 14.42 ± 0.20 15.67 ± 0.87* 14.92 ± 0.29 15.24 ± 0.52 
Neo1fl/fl;Alb-Cre− (5 wk) (n = 4)Neo1fl/fl;Alb-Cre+ (5 wk) (n = 7)Neo1fl/fl;Alb-Cre− (8 wk) (n = 6)Neo1fllwt;Alb-Cre+ (8 wk) (n = 5)Neo1fl/fl;Alb-Cre+ (8 wk) (n = 8)Neo1fl/fl;Alb-Cre− (15 wk) (n = 4)Neo1fl/fl;Alb-Cre+ (15 wk) (n = 5)
RBC 8.57 ± 0.17 8.48 ± 0.25 8.83 ± 0.40 8.98 ± 0.33 8.83 ± 0.41 9.19 ± 0.51 9.15 ± 0.48 
Hb 12.65 ± 0.24 12.95 ± 0.15* 12.76 ± 0.51 12.90 ± 0.61 13.81 ± 0.36† 13.57 ± 0.35 13.90 ± 0.36 
HCT 42.72 ± 0.55 44.18 ± 0.81* 40.06 ± 1.49 40.86 ± 3.03 43.93 ± 1.47† 42.35 ± 2.26 44.60 ± 2.47 
MCV 48.40 ± 0.39 50.40 ± 1.66* 45.36 ± 1.16 45.86 ± 0.28 49.81 ± 1.64† 46.10 ± 1.48 48.70 ± 0.63* 
MCH 14.40 ± 0.28 14.85 ± 0.29* 14.45 ± 0.58 14.42 ± 0.20 15.67 ± 0.87* 14.92 ± 0.29 15.24 ± 0.52 

Data are expressed as means ± SD. Two-tailed Student t test was used for statistical analysis between Neo1fl/wt;Alb-Cr+ mice and the age-matched Neo1fl/fl;Alb-Cre− control group at 5 and 15 wk old. One-way ANOVA and Tukey’s posttest were used to compare 8-wk-old mice.

*

P < .05.

†

P < .001.

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