Table 1. Hematological parameters in... | American Society of Hematology

Table 1.

Hematological parameters in Jak2^Plt−/− mice

Parameter	Jak2^Plt+/+	Jak2^Plt−/−	P
Platelets
Platelets, 10³/µL	1520 ± 167	7544 ± 1013	<.001
MPV, fL	6.68 ± 0.23	6.73 ± 0.15	.568
IPF, %	4.55 ± 0.66	6.00 ± 1.85	.033
Bone marrow MKs/mm²	77 ± 18	219 ± 34	<.001
Erythrocytes
Erythrocytes, 10³/µL	8500 ± 675	7933 ± 566	.065
MCV, fL	50.58 ± 0.61	51.57 ± 0.88	.011
Reticulocytes, %	2.89 ± 0.63	2.64 ± 0.85	.467
Leukocytes
Lymphocytes, 10³/µL	3.78 ± 0.57	5.33 ± 1.99	.050
Granulocytes, 10³/µL	0.80 ± 0.48	1.27 ± 0.78	.165
Monocytes, 10³/µL	0.57 ± 0.39	0.87 ± 0.39	.144
Spleen size
Spleen/body weight, mg/g	2.72 ± 0.53	5.90 ± 1.13	<.001

Parameter	Jak2^Plt+/+	Jak2^Plt−/−	P
Platelets
Platelets, 10³/µL	1520 ± 167	7544 ± 1013	<.001
MPV, fL	6.68 ± 0.23	6.73 ± 0.15	.568
IPF, %	4.55 ± 0.66	6.00 ± 1.85	.033
Bone marrow MKs/mm²	77 ± 18	219 ± 34	<.001
Erythrocytes
Erythrocytes, 10³/µL	8500 ± 675	7933 ± 566	.065
MCV, fL	50.58 ± 0.61	51.57 ± 0.88	.011
Reticulocytes, %	2.89 ± 0.63	2.64 ± 0.85	.467
Leukocytes
Lymphocytes, 10³/µL	3.78 ± 0.57	5.33 ± 1.99	.050
Granulocytes, 10³/µL	0.80 ± 0.48	1.27 ± 0.78	.165
Monocytes, 10³/µL	0.57 ± 0.39	0.87 ± 0.39	.144
Spleen size
Spleen/body weight, mg/g	2.72 ± 0.53	5.90 ± 1.13	<.001

Results are the means ± SD and are compared by using the unpaired Student t test (complete blood count: Jak2^Plt+/+ n = 10 and Jak2^Plt−/− n = 9; bone marrow MKs: Jak2^Plt+/+ n = 6 and Jak2^Plt−/− n = 6; spleen size: Jak2^Plt+/+ n = 20 and Jak2^Plt−/− n = 17). MPV, mean platelet volume; IPF, immature platelet fraction; MKs, megakaryocytes; MCV, mean corpuscular volume.

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