Table 1.

Frequency of anti-PF4/polyanion IgG in vaccinated individuals

VaccineBNT162b2ChAdOx1 nCoV-19Total
Total (%) 143 (50.9) 138 (49.1) 281 (100) 
Age, y (median) 43 45 44 
Female (%) 107 (74.8) 99 (71.7) 206 (73.3) 
Postvaccination PF4/polyanion EIA+ (%) 8 (5.5) 11 (8.0) 19 (6.8) 
SeCo substudy (n, %) 111 (47.4) 123 (52.6) 234 (100) 
Postvaccination PF4/polyanion EIA+ (%) 7* (6.3) 10* (8.1) 17* (7.3) 
Baseline samples available 
Baseline PF4/polyanion EIA+ (%) 
AICOVI substudy (n, %) 32 (68.1) 15 (31.9) 47 (100) 
Postvaccination PF4/polyanion EIA+ (%) 1 (3.1) 1 (6.7) 2 (4.3) 
Baseline PF4/polyanion EIA+ (%) 0 (0) 1 (6.7) 1 (2.1) 
VaccineBNT162b2ChAdOx1 nCoV-19Total
Total (%) 143 (50.9) 138 (49.1) 281 (100) 
Age, y (median) 43 45 44 
Female (%) 107 (74.8) 99 (71.7) 206 (73.3) 
Postvaccination PF4/polyanion EIA+ (%) 8 (5.5) 11 (8.0) 19 (6.8) 
SeCo substudy (n, %) 111 (47.4) 123 (52.6) 234 (100) 
Postvaccination PF4/polyanion EIA+ (%) 7* (6.3) 10* (8.1) 17* (7.3) 
Baseline samples available 
Baseline PF4/polyanion EIA+ (%) 
AICOVI substudy (n, %) 32 (68.1) 15 (31.9) 47 (100) 
Postvaccination PF4/polyanion EIA+ (%) 1 (3.1) 1 (6.7) 2 (4.3) 
Baseline PF4/polyanion EIA+ (%) 0 (0) 1 (6.7) 1 (2.1) 
*

Eight participants who tested positive after vaccination had no available baseline sample (4 with BNT162b2 and 4 with ChAdOx1 nCoV-19).

Only participants with positive PF4/polyanion EIA after vaccination who had an available baseline sample before vaccination were tested.

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