Complete list of copy number abnormalities and loss of heterozygosity by SNP array for each case
| Case no. . | Chromosome region . | Cytoband . | Event . | Length (Mb) . | Cytogenetic study . |
|---|---|---|---|---|---|
| 1 | chr9:204c738-36c232,413 | p24.3-p13.3 | CN-LOH | 36.03 | NA |
| chr9:21c778,976-22c081,850 | p21.3 | Homozygous deletion | 0.30 | ||
| chr9:133c510,616-133c730,353 | q34.12 | Deletion | 0.22 | ||
| chr11:192c764-51c575,951 | p15.5-p11.12 | CN-LOH | 51.38 | ||
| chr14:22c922,369-36c982,350 | q11.2-q13.3 | Deletion | 14.06 | ||
| chr17:37c291,349-80c263,427 | q12-q25.3 | CN-LOH | 42.97 | ||
| 2 | chr9:204c738-23c386,738 | p24.3-p21.3 | CN-LOH | 23.18 | NA |
| chr9:21c856,470-22c176,560 | p21.3 | Homozygous deletion | 0.32 | ||
| chr10:0-36c046,475 | p15.3-p11.21 | Gain | 36.05 | ||
| chr10:89c617,344-90c167,065 | q23.31 | High copy gain, CN = 4 | 0.55 | ||
| chr14:98c086,294-99c793,689 | q32.2 | Gain | 1.71 | ||
| chrX:0-155c270,560 | p22.33-q28 | Deletion | 155.27 | ||
| 3 | chr9:204c738-27c123,260 | p24.3-p21.2 | CN-LOH | 26.92 | 46,XY,t1,14(32P;q11.2)[6]/46XY[9] (TAL1-TCR fusion) |
| chr9:21c331,119-22c549,702 | p21.3 | Homozygous deletion | 1.22 | ||
| 4 | chr5:38c139-180c698,312 | p15.33-q35.3 | Gain | 180.66 | NA |
| chr9:19c277,320-21c853,221 | p22.1-p21.3 | Deletion | 2.58 | ||
| chr9:21c856,470-22c004,153 | p21.3 | Homozygous deletion | 0.15 | ||
| chr9:22c004,669-23c897,432 | p21.3 | Deletion | 1.89 | ||
| chr20:69c094-15c687,866 | p13-p12.1 | Gain | 15.62 | ||
| chr20:15c691,240-15c792,451 | p12.1 | Gain | 0.10 | ||
| chr20:15c795,175-62c912,463 | p12.1-q13.33 | Gain | 47.12 | ||
| 5 | chr6:135c483,742-135c754,471 | q23.3 | High copy gain, CN = 4 | 0.27 | 47,XY,t11,19(q23;p13.3), +der(19)t11,19[5]/46,XY[21]; FISH positive for MLL rearrangement in 7.5% cells |
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr10:607c980-718c912 | p15.3 | Deletion | 0.11 | ||
| chr11:118c411,424-134c938,847 | q23.3-q25 | Gain | 16.53 | ||
| chr13:32c929,387-32c952,164 | q13.1 | Gain | 0.02 | ||
| chr19:6c585c298-23c460,785 | p13.3-p12 | Gain | 16.88 | ||
| chr19:28c462,580-59c093,239 | q11-q13.43 | Gain | 30.63 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 | ||
| 6 | chr5:48c877,508-180c915,260 | q11.1-q35.3 | CN-LOH | 132.04 | NA |
| chr9:204c738-21c951,040 | p24.3-p21.3 | Deletion | 21.75 | ||
| chr9:21c953,099-25c029,497 | p21.3 | Homozygous deletion | 3.08 | ||
| chr9:25c049,865-27c722,059 | p21.3-p21.2 | Gain | 2.67 | ||
| chr13:48c984,722-49c065,037 | q14.2 | Homozygous deletion | 0.08 | ||
| chr14:36c649,246-36c949,593 | q13.3 | Deletion | 0.30 | ||
| chrX:154c979,673-155c219,364 | q28 | Deletion | 0.24 | ||
| 7 | chr4:52c657,621-191c154,276 | q11-q35.2 | Deletion | 138.50 | FISH positive for nullisomy of CDKN2A (9p21) gene in 88% cells; karyotype NA |
| chr8:0-146c364,022 | p23.3-q24.3 | Gain | 146.36 | ||
| chr9:11c311,712-13c036,747 | p23 | Deletion | 1.73 | ||
| chr9:21c242,161-21c813,718 | p21.3 | Deletion | 0.57 | ||
| chr9:21c816,528-22c655,723 | p21.3 | Homozygous deletion | 0.84 | ||
| chr9:22c669,166-23c694,188 | p21.3 | Deletion | 1.03 | ||
| chr13:19c084,823-115c103,150 | q11-q34 | Gain | 96.02 | ||
| chr15:22c752,399-102c397,317 | q11.2-q26.3 | CN-LOH | 79.64 | ||
| chr17:0-81c195,210 | p13.3-q25.3 | CN-LOH | 81.20 | ||
| chr19:247c232-10c976,405 | p13.3-p13.2 | CN-LOH | 10.73 | ||
| chr21:9c648c315-48c097,610 | p11.2-q22.3 | Gain | 38.45 | ||
| 8 | chr4:126c144,980-191c154,276 | q28.1-q35.2 | CN-LOH | 65.01 | FISH negative for BCR-ABL, karyotype NA |
| chr9:204c738-33c282,392 | p24.3-p13.3 | CN-LOH | 33.08 | ||
| chr9:21c901,263-21c993,964 | p21.3 | Homozygous deletion | 0.09 | ||
| chr16:3c892c461-4c518c754 | p13.3 | Deletion | 0.63 | ||
| 9 | chr9:62c209-19c471,279 | p24.3-p22.1 | CN-LOH | 19.41 | NA |
| chr9:19c628,633-32c741,593 | p22.1-p21.1 | Deletion | 13.11 | ||
| chr11:127c117,212-129c553,078 | q24.2-q24.3 | Deletion | 2.44 | ||
| 10 | chr9:204c738-36c489,161 | p24.3-p13.2 | CN-LOH | 36.28 | NA |
| chr9:21c827,992-22c008,313 | p21.3 | Homozygous deletion | 0.18 | ||
| 11 | chr2:144c545,138-243c052,331 | q22.3-q37.3 | CN-LOH | 98.51 | NA |
| chr2:213c584,595-214c009,831 | q34 | Deletion | 0.43 | ||
| chr9:21c901,263-21c993,468 | p21.3 | Homozygous deletion | 0.09 | ||
| chr9:21c993,964-22c098,619 | p21.3 | Deletion | 0.10 | ||
| chr9:133c719,421-134c094,802 | q34.12-q34.13 | Gain | 0.38 | ||
| chr13:48c984,722-49c065,037 | q14.2 | Homozygous deletion | 0.08 | ||
| chr13:50c652,628-51c516,305 | q14.2-q14.3 | Deletion | 0.86 | ||
| chrX:130c973,820-134c581,228 | q26.2-q26.3 | Deletion | 3.61 | ||
| 12 | chr9:131c468,740-133c828,128 | q34.11-q34.12 | Deletion | 2.36 | NA |
| 13 | chr5:162c623,390-170c762,448 | q34-q35.1 | Deletion | 8.14 | NA |
| chr9:20c678,439-21c987,472 | p21.3 | Deletion | 1.31 | ||
| chr9:21c988,896-22c207,037 | p21.3 | Homozygous deletion | 0.22 | ||
| chr11:114c990,423-118c489,708 | q23.3 | CN-LOH | 3.50 | ||
| chr14:22c187,584-107c282,024 | q11.2-q32.33 | CN-LOH | 85.09 | ||
| 14 | chr4:54c296,381-55c130,682 | q12 | Deletion | 0.83 | Normal karyotype |
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr9:21c928,654-22c114,495 | p21.3 | Deletion | 0.19 | ||
| chrX:44c810,604-44c896,206 | p11.3 | Homozygous deletion | 0.09 | ||
| 15 | chr4:54c324,930-55c102,425 | q12 | Deletion | 0.78 | NA |
| chr4:55c105,182-64c560,949 | q12-q13.1 | Deletion | 9.46 | ||
| chr4:64c573,303-83c148,663 | q13.1-q21.22 | Deletion | 18.58 | ||
| chr4:83c164,184-93c288,641 | q21.22-q22.1 | Deletion | 10.12 | ||
| chr4:92c607,449-191c154,276 | q22.1-q35.2 | CN-LOH | 98.55 | ||
| chr6:135c293,365-135c754,471 | q23.3 | High copy gain, CN = 4 | 0.46 | ||
| chr7:92c245,458-92c471,899 | q21.2 | High copy gain, CN = 4 − 5 | 0.23 | ||
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr9:21c965,073-22c014,524 | p21.3 | Homozygous deletion | 0.05 | ||
| chr9:80c446,364-80c704,731 | q21.2 | High copy gain, CN = 4 − 5 | 0.26 | ||
| chr11:128c157,643-128c615,486 | q24.3 | Gain | 0.46 | ||
| chr12:11c795,269-12c059,452 | p13.2 | Gain | 0.26 | ||
| chr13:48c885,423-49c262,256 | q14.2 | Gain | 0.38 | ||
| chr14:98c100,176-100c100,128 | q32.2 | Gain | 2.00 | ||
| chr15:56c642,839-58c955,123 | q21.3 | Gain | 2.31 | ||
| 16 | chr11:79c517,863-93c209,472 | q14.1-q21 | Deletion | 13.69 | 46,XX,t7,12(p13;p13), ?add17(p11.2)[16]/46,XX[11] |
| 17 | chr1:202c643,208-249c212,878 | q32.1-q44 | Gain | 46.57 | 51,XY,+5,del5(q31),+6, +del9(p13),?inv9(p24q21)x2, der(11)t1,11(q32;q?230,+18, +19[9]; FISH positive for 9p21 homozygous deletion in 89% cells; negative for MLL rearrangement and BCR-ABL fusion. |
| chr5:38c139-128c975,230 | p15.33-q23.3 | Gain | 128.94 | ||
| chr5:128c846,774-180c698,312 | q23.3-q35.3 | CN-LOH | 51.85 | ||
| chr6:204c909-31c553,468 | p25.3-p21.33 | Gain | 31.35 | ||
| chr6:31c555,130-32c162,418 | p21.33-p21.32 | Gain | 0.61 | ||
| chr6:32c167,778-170c913,051 | p21.32-q27 | Gain | 138.75 | ||
| chr8:138c891,978-146c292,734 | q24.23-q24.3 | Gain | 7.40 | ||
| chr9:0-12c042,349 | p24.3-p23 | CN-LOH | 12.04 | ||
| chr9:12c054,659-13c345,642 | p23 | Homozygous deletion | 1.29 | ||
| chr9:13c354,725-21c585,658 | p23-p21.3 | CN-LOH | 8.23 | ||
| chr9:21c604,067-24c075,082 | p21.3 | Homozygous deletion | 2.47 | ||
| chr9:24c044,951-38c802,685 | p21.3-p13.1 | CN-LOH | 14.76 | ||
| chr9:68c170,421-141c054,761 | q13-q34.3 | Gain | 72.88 | ||
| chr14:95c161,449-107c282,024 | q32.13-q32.33 | Gain | 12.12 | ||
| chr18:0-78c077,248 | p11.32-q23 | Gain | 78.08 | ||
| chr19:0-59c128,983 | p13.3-q13.43 | Gain | 59.13 | ||
| 18 | Normal female | NA | |||
| 19 | chr1:754c192-8c788c907 | p36.33-p36.23 | Deletion | 8.03 | NA |
| chr1:91c967,341-99c114,927 | p22.2-p21.3 | Deletion | 7.15 | ||
| chr8:172c417-17c835,685 | p23.3-p22 | Deletion | 17.66 | ||
| chr10:89c432,286-90c306,376 | q23.2-q23.31 | Deletion | 0.87 | ||
| chr11:28c057,957-49c688,837 | p14.1-p11.12 | Deletion | 21.63 | ||
| chr12:189c400-25c551,025 | p13.33-p12.1 | Deletion | 25.36 | ||
| chr12:27c498,107-32c164,030 | p11.23-p11.21 | Deletion | 4.67 | ||
| chr17:400c959-1c461c125 | p13.3 | Gain | 1.06 | ||
| chrX:41c201,762-41c531,564 | p11.4 | Homozygous deletion | 0.33 | ||
| chrX:42c869,649-44c344,324 | p11.3 | Homozygous deletion | 1.47 | ||
| chrX:45c481,094-48c206,911 | p11.3-p11.23 | Gain | 2.73 | ||
| chrX:50c817,478-52c695,241 | p11.22 | Homozygous deletion | 1.88 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 | ||
| 20 | chr6:108c974,746-110c936,144 | q21 | Deletion | 1.96 | NA |
| chr12:189c400-29c877,262 | p13.33-p11.22 | Deletion | 29.69 | ||
| 21 | chr9:148c341-21c900,510 | p24.3-p21.3 | CN-LOH | 21.75 | NA |
| chr9:21c900,511-21c971,583 | p21.3 | Homozygous deletion | 0.07 | ||
| chr9:21c971,584-34c406,287 | p21.3-p13.3 | CN-LOH | 12.43 | ||
| 22 | chr1:754c192-33c899,167 | p36.33-p35.1 | Deletion | 33.14 | NA |
| chr4:58c592,202-190c915,650 | q12-q35.2 | Deletion | 132.32 | ||
| chr5:38c139-24c037,074 | p15.33-p14.2 | Deletion | 24.00 | ||
| chr5:70c306,678-180c698,312 | q13.2-q35.3 | Deletion | 110.39 | ||
| chr7:41c421-52c432,938 | p22.3-p12.1 | Deletion | 52.39 | ||
| chr9:4c304c915-21c255,150 | p24.2-p21.3 | Deletion | 16.95 | ||
| chr9:21c265,500-25c891,012 | p21.3-p21.2 | Homozygous deletion | 4.63 | ||
| chr12:9c512c809-30c667,228 | p13.31-p11.22 | Deletion | 21.15 | ||
| chr13:36c912,708-115c103,150 | q13.3-q34 | Deletion | 78.19 | ||
| chr16:83c887-27c690,168 | p13.3-p12.1 | Deletion | 27.61 | ||
| chr18:26c057,437-78c007,784 | q12.1-q23 | Gain | 51.95 | ||
| 23 | tetraploidy | NA | |||
| chr1:3c921c449-7c050c061 | p36.32-p36.31 | Deletion, CN = 2 | 3.13 | ||
| chr1:23c103,620-24c108,104 | p36.12-p36.11 | Deletion, CN = 2 | 1.00 | ||
| chr1:114c594,372-115c470,556 | p13.2 | Deletion, CN = 2 | 0.88 | ||
| chr2:54c374,691-55c005,224 | p16.2-p16.1 | Deletion, CN = 2 | 0.63 | ||
| chr5:133c415,731-134c917,467 | q31.1 | Deletion, CN = 2 | 1.50 | ||
| chr6:0-26c382,744 | p25.3-p22.2 | CN-LOH, CN = 4 | 26.38 | ||
| chr8:33c078,287-33c503,454 | p12 | Deletion, CN = 2 | 0.43 | ||
| chr9:30c001,529-30c721,717 | p21.1 | Deletion, CN = 2 | 0.72 | ||
| chr9:133c618,461-134c097,558 | q34.12-q34.13 | High copy gain, CN = 6 | 0.48 | ||
| chr10:104c369,298-104c562,842 | q24.32 | Deletion, CN = 2 | 0.19 | ||
| chr11:103c091,553-114c475,360 | q22.3-q23.2 | Deletion, CN = 2 | 11.38 | ||
| chr12:17c200,436-18c268,880 | p12.3 | Deletion, CN = 2 | 1.07 | ||
| chr12:110c067,819-111c370,885 | q24.11 | Deletion, CN = 2 | 1.30 | ||
| chr12:111c370,885-111c911,916 | q24.11-q24.12 | Homozygous deletion, CN = 0 | 0.54 | ||
| chr12:111c911,916-112c035,561 | q24.12 | Deletion, CN = 2 | 0.12 | ||
| chr14:91c600,426-94c111,212 | q32.11-q32.12 | Deletion, CN = 2 | 2.51 | ||
| chr16:0-2c210c796 | p13.3 | Deletion, CN = 2 | 2.21 | ||
| chr16:7c299c668-8c301c002 | p13.3-p13.2 | Deletion, CN = 2 | 1.00 | ||
| chr17:27c957,832-29c631,473 | q11.2 | Deletion, CN = 2 | 1.67 | ||
| chr17:29c631,473-29c897,502 | q11.2 | Homozygous deletion, CN = 0 | 0.27 | ||
| chr17:29c897,502-30c692,775 | q11.2 | Deletion, CN = 2 | 0.80 | ||
| chr18:76c375,122-77c458,776 | q23 | Deletion, CN = 2 | 1.08 | ||
| chr20:49c176,050-53c504,956 | q13.13-q13.2 | Deletion, CN = 2 | 4.33 | ||
| chr22:37c543,717-39c369,251 | q12.3-q13.1 | Deletion, CN = 2 | 1.83 | ||
| chrX:133c432,498-134c242,874 | q26.2-q26.3 | Deletion, CN = 2 | 0.81 | ||
| 24 | chr1:754c192-9c617c682 | p36.33-p36.22 | Deletion | 8.86 | NA |
| chr2:42c280,854-50c636,065 | p21-p16.3 | Deletion | 8.36 | ||
| chr9:204c738-38c495,131 | p24.3-p13.1 | Deletion | 38.29 | ||
| chr9:68c170,421-141c054,761 | q13-q34.3 | Gain | 72.88 | ||
| chr12:189c400-6c771c877 | p13.33-p13.31 | Gain | 6.58 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 |
| Case no. . | Chromosome region . | Cytoband . | Event . | Length (Mb) . | Cytogenetic study . |
|---|---|---|---|---|---|
| 1 | chr9:204c738-36c232,413 | p24.3-p13.3 | CN-LOH | 36.03 | NA |
| chr9:21c778,976-22c081,850 | p21.3 | Homozygous deletion | 0.30 | ||
| chr9:133c510,616-133c730,353 | q34.12 | Deletion | 0.22 | ||
| chr11:192c764-51c575,951 | p15.5-p11.12 | CN-LOH | 51.38 | ||
| chr14:22c922,369-36c982,350 | q11.2-q13.3 | Deletion | 14.06 | ||
| chr17:37c291,349-80c263,427 | q12-q25.3 | CN-LOH | 42.97 | ||
| 2 | chr9:204c738-23c386,738 | p24.3-p21.3 | CN-LOH | 23.18 | NA |
| chr9:21c856,470-22c176,560 | p21.3 | Homozygous deletion | 0.32 | ||
| chr10:0-36c046,475 | p15.3-p11.21 | Gain | 36.05 | ||
| chr10:89c617,344-90c167,065 | q23.31 | High copy gain, CN = 4 | 0.55 | ||
| chr14:98c086,294-99c793,689 | q32.2 | Gain | 1.71 | ||
| chrX:0-155c270,560 | p22.33-q28 | Deletion | 155.27 | ||
| 3 | chr9:204c738-27c123,260 | p24.3-p21.2 | CN-LOH | 26.92 | 46,XY,t1,14(32P;q11.2)[6]/46XY[9] (TAL1-TCR fusion) |
| chr9:21c331,119-22c549,702 | p21.3 | Homozygous deletion | 1.22 | ||
| 4 | chr5:38c139-180c698,312 | p15.33-q35.3 | Gain | 180.66 | NA |
| chr9:19c277,320-21c853,221 | p22.1-p21.3 | Deletion | 2.58 | ||
| chr9:21c856,470-22c004,153 | p21.3 | Homozygous deletion | 0.15 | ||
| chr9:22c004,669-23c897,432 | p21.3 | Deletion | 1.89 | ||
| chr20:69c094-15c687,866 | p13-p12.1 | Gain | 15.62 | ||
| chr20:15c691,240-15c792,451 | p12.1 | Gain | 0.10 | ||
| chr20:15c795,175-62c912,463 | p12.1-q13.33 | Gain | 47.12 | ||
| 5 | chr6:135c483,742-135c754,471 | q23.3 | High copy gain, CN = 4 | 0.27 | 47,XY,t11,19(q23;p13.3), +der(19)t11,19[5]/46,XY[21]; FISH positive for MLL rearrangement in 7.5% cells |
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr10:607c980-718c912 | p15.3 | Deletion | 0.11 | ||
| chr11:118c411,424-134c938,847 | q23.3-q25 | Gain | 16.53 | ||
| chr13:32c929,387-32c952,164 | q13.1 | Gain | 0.02 | ||
| chr19:6c585c298-23c460,785 | p13.3-p12 | Gain | 16.88 | ||
| chr19:28c462,580-59c093,239 | q11-q13.43 | Gain | 30.63 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 | ||
| 6 | chr5:48c877,508-180c915,260 | q11.1-q35.3 | CN-LOH | 132.04 | NA |
| chr9:204c738-21c951,040 | p24.3-p21.3 | Deletion | 21.75 | ||
| chr9:21c953,099-25c029,497 | p21.3 | Homozygous deletion | 3.08 | ||
| chr9:25c049,865-27c722,059 | p21.3-p21.2 | Gain | 2.67 | ||
| chr13:48c984,722-49c065,037 | q14.2 | Homozygous deletion | 0.08 | ||
| chr14:36c649,246-36c949,593 | q13.3 | Deletion | 0.30 | ||
| chrX:154c979,673-155c219,364 | q28 | Deletion | 0.24 | ||
| 7 | chr4:52c657,621-191c154,276 | q11-q35.2 | Deletion | 138.50 | FISH positive for nullisomy of CDKN2A (9p21) gene in 88% cells; karyotype NA |
| chr8:0-146c364,022 | p23.3-q24.3 | Gain | 146.36 | ||
| chr9:11c311,712-13c036,747 | p23 | Deletion | 1.73 | ||
| chr9:21c242,161-21c813,718 | p21.3 | Deletion | 0.57 | ||
| chr9:21c816,528-22c655,723 | p21.3 | Homozygous deletion | 0.84 | ||
| chr9:22c669,166-23c694,188 | p21.3 | Deletion | 1.03 | ||
| chr13:19c084,823-115c103,150 | q11-q34 | Gain | 96.02 | ||
| chr15:22c752,399-102c397,317 | q11.2-q26.3 | CN-LOH | 79.64 | ||
| chr17:0-81c195,210 | p13.3-q25.3 | CN-LOH | 81.20 | ||
| chr19:247c232-10c976,405 | p13.3-p13.2 | CN-LOH | 10.73 | ||
| chr21:9c648c315-48c097,610 | p11.2-q22.3 | Gain | 38.45 | ||
| 8 | chr4:126c144,980-191c154,276 | q28.1-q35.2 | CN-LOH | 65.01 | FISH negative for BCR-ABL, karyotype NA |
| chr9:204c738-33c282,392 | p24.3-p13.3 | CN-LOH | 33.08 | ||
| chr9:21c901,263-21c993,964 | p21.3 | Homozygous deletion | 0.09 | ||
| chr16:3c892c461-4c518c754 | p13.3 | Deletion | 0.63 | ||
| 9 | chr9:62c209-19c471,279 | p24.3-p22.1 | CN-LOH | 19.41 | NA |
| chr9:19c628,633-32c741,593 | p22.1-p21.1 | Deletion | 13.11 | ||
| chr11:127c117,212-129c553,078 | q24.2-q24.3 | Deletion | 2.44 | ||
| 10 | chr9:204c738-36c489,161 | p24.3-p13.2 | CN-LOH | 36.28 | NA |
| chr9:21c827,992-22c008,313 | p21.3 | Homozygous deletion | 0.18 | ||
| 11 | chr2:144c545,138-243c052,331 | q22.3-q37.3 | CN-LOH | 98.51 | NA |
| chr2:213c584,595-214c009,831 | q34 | Deletion | 0.43 | ||
| chr9:21c901,263-21c993,468 | p21.3 | Homozygous deletion | 0.09 | ||
| chr9:21c993,964-22c098,619 | p21.3 | Deletion | 0.10 | ||
| chr9:133c719,421-134c094,802 | q34.12-q34.13 | Gain | 0.38 | ||
| chr13:48c984,722-49c065,037 | q14.2 | Homozygous deletion | 0.08 | ||
| chr13:50c652,628-51c516,305 | q14.2-q14.3 | Deletion | 0.86 | ||
| chrX:130c973,820-134c581,228 | q26.2-q26.3 | Deletion | 3.61 | ||
| 12 | chr9:131c468,740-133c828,128 | q34.11-q34.12 | Deletion | 2.36 | NA |
| 13 | chr5:162c623,390-170c762,448 | q34-q35.1 | Deletion | 8.14 | NA |
| chr9:20c678,439-21c987,472 | p21.3 | Deletion | 1.31 | ||
| chr9:21c988,896-22c207,037 | p21.3 | Homozygous deletion | 0.22 | ||
| chr11:114c990,423-118c489,708 | q23.3 | CN-LOH | 3.50 | ||
| chr14:22c187,584-107c282,024 | q11.2-q32.33 | CN-LOH | 85.09 | ||
| 14 | chr4:54c296,381-55c130,682 | q12 | Deletion | 0.83 | Normal karyotype |
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr9:21c928,654-22c114,495 | p21.3 | Deletion | 0.19 | ||
| chrX:44c810,604-44c896,206 | p11.3 | Homozygous deletion | 0.09 | ||
| 15 | chr4:54c324,930-55c102,425 | q12 | Deletion | 0.78 | NA |
| chr4:55c105,182-64c560,949 | q12-q13.1 | Deletion | 9.46 | ||
| chr4:64c573,303-83c148,663 | q13.1-q21.22 | Deletion | 18.58 | ||
| chr4:83c164,184-93c288,641 | q21.22-q22.1 | Deletion | 10.12 | ||
| chr4:92c607,449-191c154,276 | q22.1-q35.2 | CN-LOH | 98.55 | ||
| chr6:135c293,365-135c754,471 | q23.3 | High copy gain, CN = 4 | 0.46 | ||
| chr7:92c245,458-92c471,899 | q21.2 | High copy gain, CN = 4 − 5 | 0.23 | ||
| chr9:204c738-39c184,065 | p24.3-p13.1 | CN-LOH | 38.98 | ||
| chr9:21c965,073-22c014,524 | p21.3 | Homozygous deletion | 0.05 | ||
| chr9:80c446,364-80c704,731 | q21.2 | High copy gain, CN = 4 − 5 | 0.26 | ||
| chr11:128c157,643-128c615,486 | q24.3 | Gain | 0.46 | ||
| chr12:11c795,269-12c059,452 | p13.2 | Gain | 0.26 | ||
| chr13:48c885,423-49c262,256 | q14.2 | Gain | 0.38 | ||
| chr14:98c100,176-100c100,128 | q32.2 | Gain | 2.00 | ||
| chr15:56c642,839-58c955,123 | q21.3 | Gain | 2.31 | ||
| 16 | chr11:79c517,863-93c209,472 | q14.1-q21 | Deletion | 13.69 | 46,XX,t7,12(p13;p13), ?add17(p11.2)[16]/46,XX[11] |
| 17 | chr1:202c643,208-249c212,878 | q32.1-q44 | Gain | 46.57 | 51,XY,+5,del5(q31),+6, +del9(p13),?inv9(p24q21)x2, der(11)t1,11(q32;q?230,+18, +19[9]; FISH positive for 9p21 homozygous deletion in 89% cells; negative for MLL rearrangement and BCR-ABL fusion. |
| chr5:38c139-128c975,230 | p15.33-q23.3 | Gain | 128.94 | ||
| chr5:128c846,774-180c698,312 | q23.3-q35.3 | CN-LOH | 51.85 | ||
| chr6:204c909-31c553,468 | p25.3-p21.33 | Gain | 31.35 | ||
| chr6:31c555,130-32c162,418 | p21.33-p21.32 | Gain | 0.61 | ||
| chr6:32c167,778-170c913,051 | p21.32-q27 | Gain | 138.75 | ||
| chr8:138c891,978-146c292,734 | q24.23-q24.3 | Gain | 7.40 | ||
| chr9:0-12c042,349 | p24.3-p23 | CN-LOH | 12.04 | ||
| chr9:12c054,659-13c345,642 | p23 | Homozygous deletion | 1.29 | ||
| chr9:13c354,725-21c585,658 | p23-p21.3 | CN-LOH | 8.23 | ||
| chr9:21c604,067-24c075,082 | p21.3 | Homozygous deletion | 2.47 | ||
| chr9:24c044,951-38c802,685 | p21.3-p13.1 | CN-LOH | 14.76 | ||
| chr9:68c170,421-141c054,761 | q13-q34.3 | Gain | 72.88 | ||
| chr14:95c161,449-107c282,024 | q32.13-q32.33 | Gain | 12.12 | ||
| chr18:0-78c077,248 | p11.32-q23 | Gain | 78.08 | ||
| chr19:0-59c128,983 | p13.3-q13.43 | Gain | 59.13 | ||
| 18 | Normal female | NA | |||
| 19 | chr1:754c192-8c788c907 | p36.33-p36.23 | Deletion | 8.03 | NA |
| chr1:91c967,341-99c114,927 | p22.2-p21.3 | Deletion | 7.15 | ||
| chr8:172c417-17c835,685 | p23.3-p22 | Deletion | 17.66 | ||
| chr10:89c432,286-90c306,376 | q23.2-q23.31 | Deletion | 0.87 | ||
| chr11:28c057,957-49c688,837 | p14.1-p11.12 | Deletion | 21.63 | ||
| chr12:189c400-25c551,025 | p13.33-p12.1 | Deletion | 25.36 | ||
| chr12:27c498,107-32c164,030 | p11.23-p11.21 | Deletion | 4.67 | ||
| chr17:400c959-1c461c125 | p13.3 | Gain | 1.06 | ||
| chrX:41c201,762-41c531,564 | p11.4 | Homozygous deletion | 0.33 | ||
| chrX:42c869,649-44c344,324 | p11.3 | Homozygous deletion | 1.47 | ||
| chrX:45c481,094-48c206,911 | p11.3-p11.23 | Gain | 2.73 | ||
| chrX:50c817,478-52c695,241 | p11.22 | Homozygous deletion | 1.88 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 | ||
| 20 | chr6:108c974,746-110c936,144 | q21 | Deletion | 1.96 | NA |
| chr12:189c400-29c877,262 | p13.33-p11.22 | Deletion | 29.69 | ||
| 21 | chr9:148c341-21c900,510 | p24.3-p21.3 | CN-LOH | 21.75 | NA |
| chr9:21c900,511-21c971,583 | p21.3 | Homozygous deletion | 0.07 | ||
| chr9:21c971,584-34c406,287 | p21.3-p13.3 | CN-LOH | 12.43 | ||
| 22 | chr1:754c192-33c899,167 | p36.33-p35.1 | Deletion | 33.14 | NA |
| chr4:58c592,202-190c915,650 | q12-q35.2 | Deletion | 132.32 | ||
| chr5:38c139-24c037,074 | p15.33-p14.2 | Deletion | 24.00 | ||
| chr5:70c306,678-180c698,312 | q13.2-q35.3 | Deletion | 110.39 | ||
| chr7:41c421-52c432,938 | p22.3-p12.1 | Deletion | 52.39 | ||
| chr9:4c304c915-21c255,150 | p24.2-p21.3 | Deletion | 16.95 | ||
| chr9:21c265,500-25c891,012 | p21.3-p21.2 | Homozygous deletion | 4.63 | ||
| chr12:9c512c809-30c667,228 | p13.31-p11.22 | Deletion | 21.15 | ||
| chr13:36c912,708-115c103,150 | q13.3-q34 | Deletion | 78.19 | ||
| chr16:83c887-27c690,168 | p13.3-p12.1 | Deletion | 27.61 | ||
| chr18:26c057,437-78c007,784 | q12.1-q23 | Gain | 51.95 | ||
| 23 | tetraploidy | NA | |||
| chr1:3c921c449-7c050c061 | p36.32-p36.31 | Deletion, CN = 2 | 3.13 | ||
| chr1:23c103,620-24c108,104 | p36.12-p36.11 | Deletion, CN = 2 | 1.00 | ||
| chr1:114c594,372-115c470,556 | p13.2 | Deletion, CN = 2 | 0.88 | ||
| chr2:54c374,691-55c005,224 | p16.2-p16.1 | Deletion, CN = 2 | 0.63 | ||
| chr5:133c415,731-134c917,467 | q31.1 | Deletion, CN = 2 | 1.50 | ||
| chr6:0-26c382,744 | p25.3-p22.2 | CN-LOH, CN = 4 | 26.38 | ||
| chr8:33c078,287-33c503,454 | p12 | Deletion, CN = 2 | 0.43 | ||
| chr9:30c001,529-30c721,717 | p21.1 | Deletion, CN = 2 | 0.72 | ||
| chr9:133c618,461-134c097,558 | q34.12-q34.13 | High copy gain, CN = 6 | 0.48 | ||
| chr10:104c369,298-104c562,842 | q24.32 | Deletion, CN = 2 | 0.19 | ||
| chr11:103c091,553-114c475,360 | q22.3-q23.2 | Deletion, CN = 2 | 11.38 | ||
| chr12:17c200,436-18c268,880 | p12.3 | Deletion, CN = 2 | 1.07 | ||
| chr12:110c067,819-111c370,885 | q24.11 | Deletion, CN = 2 | 1.30 | ||
| chr12:111c370,885-111c911,916 | q24.11-q24.12 | Homozygous deletion, CN = 0 | 0.54 | ||
| chr12:111c911,916-112c035,561 | q24.12 | Deletion, CN = 2 | 0.12 | ||
| chr14:91c600,426-94c111,212 | q32.11-q32.12 | Deletion, CN = 2 | 2.51 | ||
| chr16:0-2c210c796 | p13.3 | Deletion, CN = 2 | 2.21 | ||
| chr16:7c299c668-8c301c002 | p13.3-p13.2 | Deletion, CN = 2 | 1.00 | ||
| chr17:27c957,832-29c631,473 | q11.2 | Deletion, CN = 2 | 1.67 | ||
| chr17:29c631,473-29c897,502 | q11.2 | Homozygous deletion, CN = 0 | 0.27 | ||
| chr17:29c897,502-30c692,775 | q11.2 | Deletion, CN = 2 | 0.80 | ||
| chr18:76c375,122-77c458,776 | q23 | Deletion, CN = 2 | 1.08 | ||
| chr20:49c176,050-53c504,956 | q13.13-q13.2 | Deletion, CN = 2 | 4.33 | ||
| chr22:37c543,717-39c369,251 | q12.3-q13.1 | Deletion, CN = 2 | 1.83 | ||
| chrX:133c432,498-134c242,874 | q26.2-q26.3 | Deletion, CN = 2 | 0.81 | ||
| 24 | chr1:754c192-9c617c682 | p36.33-p36.22 | Deletion | 8.86 | NA |
| chr2:42c280,854-50c636,065 | p21-p16.3 | Deletion | 8.36 | ||
| chr9:204c738-38c495,131 | p24.3-p13.1 | Deletion | 38.29 | ||
| chr9:68c170,421-141c054,761 | q13-q34.3 | Gain | 72.88 | ||
| chr12:189c400-6c771c877 | p13.33-p13.31 | Gain | 6.58 | ||
| chrX:154c979,673-155c219,364 | q28 | Gain | 0.24 |
The last column includes karyotype and/or FISH data when available. Cases 1-15 are non-ETP T-LLy; cases 16-24 are ETP-LLy.
NA, not available.