Table 2.

Adverse prognostic factors in AITL

Adverse prognostic factorIPI22 PIT23 PIAI4 AITL score
Age ≥60 y + + + + 
ECOG >2 + + + + 
LDH > ULN + +   
Stage III-IV +  +  
Extranodal sites ≥2 +    
Bone marrow involvement  +   
B symptoms   +  
Lymphopenia (<1000/mm3)   +  
Thrombocytopenia (<150 000/mm3)   +  
CRP > ULN    + 
β2M > ULN    + 
Adverse prognostic factorIPI22 PIT23 PIAI4 AITL score
Age ≥60 y + + + + 
ECOG >2 + + + + 
LDH > ULN + +   
Stage III-IV +  +  
Extranodal sites ≥2 +    
Bone marrow involvement  +   
B symptoms   +  
Lymphopenia (<1000/mm3)   +  
Thrombocytopenia (<150 000/mm3)   +  
CRP > ULN    + 
β2M > ULN    + 
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