Table 1 Transcripts upregulated or... | American Society of Hematology

Table 1

Transcripts upregulated or downregulated ≥2.5-fold by costimulation with poly(I:C) and thrombin, relative to poly(I:C) alone

Gene	Poly(I:C) + thrombin vs control	Poly(I:C) vs control	Thrombin vs control	Poly(I:C) + thrombin vs poly(I:C)	Poly(I:C) + thrombin vs thrombin
SELE	13.12	3.85	4.14	3.41	3.17
VCAM1	9.72	2.79	3.09	3.48	3.15
CXCL8	6.66	1.88	3.4	3.54	1.96
F3	6.47	−1.33	2.36	8.59	2.74
CXCL2	5.46	1.86	1.91	2.94	2.86
NR4A1	4.32	−1.52	4.42	6.53	0.98
CXCL3	4.22	1.22	2.24	3.46	1.88
IL6	3.14	1.12	1.8	2.8	1.74
MUC16	3.03	−1.2	−1.28	3.64	3.88
C11orf96	3.01	−1.18	1.62	3.54	1.86
CCL20	3.01	1.01	2.02	3	1.49
PTGS2	2.85	−1.02	2.43	2.9	1.17
HLX	2.83	−1.06	3.23	3	0.88
NR4A2	2.78	−1.45	2.17	4.02	1.28
FST	2.68	−1.16	2.92	3.1	0.92
PMCH	2.64	−1.54	3	4.06	0.88
RCAN1	2.57	−1.11	2.08	2.85	1.24
ADGB	2.46	−1.22	−1.08	3.01	2.66
BCL2A1	2.42	−1.39	1.59	3.37	1.52
UBE3D	2.38	−1.12	−1.25	2.68	2.98
DKK2	2.31	−1.56	2.06	3.61	1.12
CD1E	2.1	−1.22	−1.22	2.57	2.56
LBH	1.8	−1.43	2.59	2.56	0.69
IL11	1.74	−1.47	2.28	2.56	0.76
CYSLTR2	−1.96	1.31	−1.39	−2.58	1.41
TRIL	−2.94	−1.14	−1.96	−2.58	1.50

Gene	Poly(I:C) + thrombin vs control	Poly(I:C) vs control	Thrombin vs control	Poly(I:C) + thrombin vs poly(I:C)	Poly(I:C) + thrombin vs thrombin
SELE	13.12	3.85	4.14	3.41	3.17
VCAM1	9.72	2.79	3.09	3.48	3.15
CXCL8	6.66	1.88	3.4	3.54	1.96
F3	6.47	−1.33	2.36	8.59	2.74
CXCL2	5.46	1.86	1.91	2.94	2.86
NR4A1	4.32	−1.52	4.42	6.53	0.98
CXCL3	4.22	1.22	2.24	3.46	1.88
IL6	3.14	1.12	1.8	2.8	1.74
MUC16	3.03	−1.2	−1.28	3.64	3.88
C11orf96	3.01	−1.18	1.62	3.54	1.86
CCL20	3.01	1.01	2.02	3	1.49
PTGS2	2.85	−1.02	2.43	2.9	1.17
HLX	2.83	−1.06	3.23	3	0.88
NR4A2	2.78	−1.45	2.17	4.02	1.28
FST	2.68	−1.16	2.92	3.1	0.92
PMCH	2.64	−1.54	3	4.06	0.88
RCAN1	2.57	−1.11	2.08	2.85	1.24
ADGB	2.46	−1.22	−1.08	3.01	2.66
BCL2A1	2.42	−1.39	1.59	3.37	1.52
UBE3D	2.38	−1.12	−1.25	2.68	2.98
DKK2	2.31	−1.56	2.06	3.61	1.12
CD1E	2.1	−1.22	−1.22	2.57	2.56
LBH	1.8	−1.43	2.59	2.56	0.69
IL11	1.74	−1.47	2.28	2.56	0.76
CYSLTR2	−1.96	1.31	−1.39	−2.58	1.41
TRIL	−2.94	−1.14	−1.96	−2.58	1.50

All genes were differentially expressed with an P_adj. ≤ .05, measured with DESeq2 v1.22.1.