Multivariable analysis using cox proportional hazards model, adjusting for ISS and FISH risk and depth of response achieved posttransplant
Variable . | TTP . | OS . | ||
---|---|---|---|---|
Hazard ratio . | P . | Hazard ratio . | P . | |
Day 100 PET+ | 1.84 (1.2-2.8) | 0.006 | 1.9 (1.1-3.2) | 0.016 |
ISS stage 3 | 1.77 (1.2-2.7) | 0.009 | 1.24 (0.76-2.0) | 0.38 |
High risk FISH | 1.34 (0.81-2.24) | 0.25 | 1.74 (1.0-3.0) | 0.049 |
Depth of response (CR) | 2.24 (1.2-4.1) | 0.009 | 1.31 (0.69-2.5) | 0.41 |
Variable . | TTP . | OS . | ||
---|---|---|---|---|
Hazard ratio . | P . | Hazard ratio . | P . | |
Day 100 PET+ | 1.84 (1.2-2.8) | 0.006 | 1.9 (1.1-3.2) | 0.016 |
ISS stage 3 | 1.77 (1.2-2.7) | 0.009 | 1.24 (0.76-2.0) | 0.38 |
High risk FISH | 1.34 (0.81-2.24) | 0.25 | 1.74 (1.0-3.0) | 0.049 |
Depth of response (CR) | 2.24 (1.2-4.1) | 0.009 | 1.31 (0.69-2.5) | 0.41 |
ISS, International Staging System; FISH, fluorescence in situ hybridization; CR, complete response.