Number of patients with grade ≥3 toxicities (day −7 to day +100)
. | Total . | Age 60-69 (%) . | Age ≥70 (%) . |
---|---|---|---|
Sample size | 346 (100) | 279 (80.6) | 67 (19.4) |
Number of patients with grade ≥ 3 toxicities day −7 to day 100 post-HCT | 323 (93) | 256 (92) | 67 (100) |
Febrile neutropenia (no source) | 218 (63) | 171 (61) | 47 (70) |
Infection | 108 (31) | 85 (30) | 23 (34) |
Oral/GI | 178 (51) | 139 (50) | 39 (58) |
Cardiovascular | 99 (29) | 61 (22) | 38 (57) |
Pulmonary | 39 (11) | 29 (10) | 10 (15) |
Metabolic | 34 (9.8) | 22 (7.9) | 12 (17.9) |
Skin | 24 (6.9) | 15 (5.4) | 9 (13) |
Neurologic | 15 (4.3) | 10 (3.6) | 5 (7.5) |
Renal | 11 (3.2) | 8 (2.9) | 3 (4.5) |
Hematologic | 12 (3.5) | 5 (1.8) | 7 (10.4) |
Hepatic | 5 (1.4) | 4 (1.4) | 1 (1.5) |
Immune | 3 (0.9) | 1 (0.4) | 2 (3.0) |
Musculoskeletal and connective tissue | 5 (1.4) | 3 (1.1) | 2 (3.0) |
Other | 6 (1.7) | 0 | 6 (9.0) |
No. of individual grade ≥ 3 toxicities per patient, median (range) | 2 (0-13) | 2 (0-10) | 3 (1-13) |
. | Total . | Age 60-69 (%) . | Age ≥70 (%) . |
---|---|---|---|
Sample size | 346 (100) | 279 (80.6) | 67 (19.4) |
Number of patients with grade ≥ 3 toxicities day −7 to day 100 post-HCT | 323 (93) | 256 (92) | 67 (100) |
Febrile neutropenia (no source) | 218 (63) | 171 (61) | 47 (70) |
Infection | 108 (31) | 85 (30) | 23 (34) |
Oral/GI | 178 (51) | 139 (50) | 39 (58) |
Cardiovascular | 99 (29) | 61 (22) | 38 (57) |
Pulmonary | 39 (11) | 29 (10) | 10 (15) |
Metabolic | 34 (9.8) | 22 (7.9) | 12 (17.9) |
Skin | 24 (6.9) | 15 (5.4) | 9 (13) |
Neurologic | 15 (4.3) | 10 (3.6) | 5 (7.5) |
Renal | 11 (3.2) | 8 (2.9) | 3 (4.5) |
Hematologic | 12 (3.5) | 5 (1.8) | 7 (10.4) |
Hepatic | 5 (1.4) | 4 (1.4) | 1 (1.5) |
Immune | 3 (0.9) | 1 (0.4) | 2 (3.0) |
Musculoskeletal and connective tissue | 5 (1.4) | 3 (1.1) | 2 (3.0) |
Other | 6 (1.7) | 0 | 6 (9.0) |
No. of individual grade ≥ 3 toxicities per patient, median (range) | 2 (0-13) | 2 (0-10) | 3 (1-13) |
Unless otherwise noted, all data are n (%).