Patient baseline characteristics
| Patient characteristics . | Total . | Age 60 to 69 y . | Age ≥70 y . | p . |
|---|---|---|---|---|
| Sample size, n (%) | 346 (100) | 279 (80.6) | 67 (19.4) | |
| Females, n (%) | 118 (34) | 97 (34) | 21 (31) | .6 |
| Age at HCT, median (range), y | 65.8 (60-77) | 64.8 (60-69.9) | 71.8 (70-77) | <.001 |
| Histology and status at HCT, n (%) | .7* | |||
| DLBCL | 136 (39) | 110 (39) | 26 (38) | |
| CR1 | 5 (4) | 5 (4.5) | 0 | |
| ≥CR2 | 102 (75) | 82 (74.5) | 20 (77) | |
| PR | 29 (21) | 23 (21) | 6 (23) | |
| MCL | 119 (34) | 99 (35) | 20 (30) | |
| CR1 | 95 (80) | 80 (81) | 15 (75) | |
| ≥CR2 | 13 (11) | 10 (10) | 3 (15) | |
| PR | 11 (9) | 9 (9) | 2 (10) | |
| FL | 21 (6.1) | 17 (6.1) | 4 (6.0) | |
| CR1 | 0 | 0 | 0 | |
| ≥CR2 | 16 (76) | 12 (71) | 4 (100) | |
| PR | 5 (24) | 5 (30) | 0 | |
| TCL | 61 (18) | 47 (17) | 14 (21) | |
| CR1 | 52 (85) | 40 (85) | 12 (86) | |
| CR2 | 3 (5) | 3 (7) | 0 | |
| PR | 6 (10) | 4 (8) | 2 (14) | |
| Other NHL | 9 (2.6) | 6 (2.2) | 3 (4.5) | |
| CR1 | 3 (33) | 2 (33) | 1 (33) | |
| ≥CR2 | 6 (67) | 4 (67) | 2 (66) | |
| Transplant in first remission | 179 (52) | 145 (52) | 34 (51) | .9 |
| Lines of therapy | .2 | |||
| 1 | 157 (45) | 127 (46) | 30 (45) | |
| 2 | 148 (43) | 115 (41) | 33 (49) | |
| ≥3 | 41 (12) | 37 (13) | 4 (6.0) | |
| Prior rituximab | 278 (80) | 225 (81) | 53 (79) | .8 |
| History of radiation | 37 (11) | 33 (12) | 4 (6.0) | .2 |
| HCT-CI, median (range) | 3 (0-10) | 3 (0-10) | 3 (0-10) | .4† |
| Low (0) | 61 (17) | 48 (17) | 13 (19) | |
| Intermediate (1-2) | 89 (26) | 75 (27) | 14 (21) | |
| High (≥3) | 196 (57) | 156 (56) | 40 (60) | |
| KPS | >.9 | |||
| ≥90 | 212 (62) | 171 (62) | 41 (62) | |
| <90 | 130 (38) | 105 (38) | 25 (38) | |
| Missing | 4 (1.1) | 3 (1.07) | 1 (1.5) | |
| Albumin (g/dL) at HCT, median (range) | 4.1 (2.8-5) | 4.1 (2.8-5) | 4.1 (3.7-4.7) | .6 |
| Absolute lymphocyte count (103/μL), median (range) | 0.5 (0.1-2.8) | 0.5 (0.1-2.8) | 0.4 (0.1-1.6) | .6 |
| Stem cell dose (CD34/kg (×106), median (range) | 5.05 (1.70-14.70) | 5.16 (1.90-14.70) | 4.80 (1.70-9.80) | .3 |
| Patient characteristics . | Total . | Age 60 to 69 y . | Age ≥70 y . | p . |
|---|---|---|---|---|
| Sample size, n (%) | 346 (100) | 279 (80.6) | 67 (19.4) | |
| Females, n (%) | 118 (34) | 97 (34) | 21 (31) | .6 |
| Age at HCT, median (range), y | 65.8 (60-77) | 64.8 (60-69.9) | 71.8 (70-77) | <.001 |
| Histology and status at HCT, n (%) | .7* | |||
| DLBCL | 136 (39) | 110 (39) | 26 (38) | |
| CR1 | 5 (4) | 5 (4.5) | 0 | |
| ≥CR2 | 102 (75) | 82 (74.5) | 20 (77) | |
| PR | 29 (21) | 23 (21) | 6 (23) | |
| MCL | 119 (34) | 99 (35) | 20 (30) | |
| CR1 | 95 (80) | 80 (81) | 15 (75) | |
| ≥CR2 | 13 (11) | 10 (10) | 3 (15) | |
| PR | 11 (9) | 9 (9) | 2 (10) | |
| FL | 21 (6.1) | 17 (6.1) | 4 (6.0) | |
| CR1 | 0 | 0 | 0 | |
| ≥CR2 | 16 (76) | 12 (71) | 4 (100) | |
| PR | 5 (24) | 5 (30) | 0 | |
| TCL | 61 (18) | 47 (17) | 14 (21) | |
| CR1 | 52 (85) | 40 (85) | 12 (86) | |
| CR2 | 3 (5) | 3 (7) | 0 | |
| PR | 6 (10) | 4 (8) | 2 (14) | |
| Other NHL | 9 (2.6) | 6 (2.2) | 3 (4.5) | |
| CR1 | 3 (33) | 2 (33) | 1 (33) | |
| ≥CR2 | 6 (67) | 4 (67) | 2 (66) | |
| Transplant in first remission | 179 (52) | 145 (52) | 34 (51) | .9 |
| Lines of therapy | .2 | |||
| 1 | 157 (45) | 127 (46) | 30 (45) | |
| 2 | 148 (43) | 115 (41) | 33 (49) | |
| ≥3 | 41 (12) | 37 (13) | 4 (6.0) | |
| Prior rituximab | 278 (80) | 225 (81) | 53 (79) | .8 |
| History of radiation | 37 (11) | 33 (12) | 4 (6.0) | .2 |
| HCT-CI, median (range) | 3 (0-10) | 3 (0-10) | 3 (0-10) | .4† |
| Low (0) | 61 (17) | 48 (17) | 13 (19) | |
| Intermediate (1-2) | 89 (26) | 75 (27) | 14 (21) | |
| High (≥3) | 196 (57) | 156 (56) | 40 (60) | |
| KPS | >.9 | |||
| ≥90 | 212 (62) | 171 (62) | 41 (62) | |
| <90 | 130 (38) | 105 (38) | 25 (38) | |
| Missing | 4 (1.1) | 3 (1.07) | 1 (1.5) | |
| Albumin (g/dL) at HCT, median (range) | 4.1 (2.8-5) | 4.1 (2.8-5) | 4.1 (3.7-4.7) | .6 |
| Absolute lymphocyte count (103/μL), median (range) | 0.5 (0.1-2.8) | 0.5 (0.1-2.8) | 0.4 (0.1-1.6) | .6 |
| Stem cell dose (CD34/kg (×106), median (range) | 5.05 (1.70-14.70) | 5.16 (1.90-14.70) | 4.80 (1.70-9.80) | .3 |