Table 5.

Effect of demographic characteristics, clinical phenotype, and fibrinogen supplementation on the total HRQoL score according to multivariate analysis

VariableMean difference in HRQoL total scoreP95% CI
Age, adult −5.7 .018 −10.4; −1.0 
Male 2.0 .369 −2.4; 6.5 
Continent, Asia-Africa 10.6 <.001 4.9; 16.4 
Distance from treatment center >100 km −3.7 .130 −8.6; 1.1 
ISTH BAT (continuous) 0.2 .038 0.0; 0.5 
Thrombotic phenotype 7.5 .017 1.4; 13.6 
Availability of fibrinogen concentrate or cryoprecipitate −6.8 .108 −15.1; 1.5 
VariableMean difference in HRQoL total scoreP95% CI
Age, adult −5.7 .018 −10.4; −1.0 
Male 2.0 .369 −2.4; 6.5 
Continent, Asia-Africa 10.6 <.001 4.9; 16.4 
Distance from treatment center >100 km −3.7 .130 −8.6; 1.1 
ISTH BAT (continuous) 0.2 .038 0.0; 0.5 
Thrombotic phenotype 7.5 .017 1.4; 13.6 
Availability of fibrinogen concentrate or cryoprecipitate −6.8 .108 −15.1; 1.5 

CI, confidence interval.

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