MCL: prognostic factors at diagnosis
| Biomarker . | Favorable . | Unfavorable . |
|---|---|---|
| MIPI or MIPI-c score | Low | High |
| Ki-67 score | <30% | ≥30% |
| Chromosome 17p | Intact | Deleted |
| TP53 | Wild-type | Mutated |
| Clinical/morphologic | Leukemic/non-nodal subtype | Blastoid or pleomorphic MCL |
| Postinduction MRD | Negative | Positive |
| MCL35 proliferation assay | Low risk | High risk |
| Anti-LRPAP1 seropositive (proposed) | Present |
| Biomarker . | Favorable . | Unfavorable . |
|---|---|---|
| MIPI or MIPI-c score | Low | High |
| Ki-67 score | <30% | ≥30% |
| Chromosome 17p | Intact | Deleted |
| TP53 | Wild-type | Mutated |
| Clinical/morphologic | Leukemic/non-nodal subtype | Blastoid or pleomorphic MCL |
| Postinduction MRD | Negative | Positive |
| MCL35 proliferation assay | Low risk | High risk |
| Anti-LRPAP1 seropositive (proposed) | Present |