AEs occurring in ≥15% of patients
| . | All treated patients (N = 99) . | |||
|---|---|---|---|---|
| AE, n (%)* . | All grades . | Grade 1 . | Grade 2 . | Grade 3 . |
| Diarrhea | 51 (51) | 37 (37) | 9 (9) | 5 (5) |
| Headache | 45 (45) | 34 (34) | 6 (6) | 5 (5) |
| Upper respiratory tract infection | 44 (44) | 5 (5) | 38 (38) | 1 (1) |
| Arthralgia | 42 (42) | 29 (29) | 12 (12) | 1 (1) |
| Contusion | 42 (42) | 38 (38) | 4 (4) | 0 |
| Weight increased | 32 (32) | 15 (15) | 14 (14) | 3 (3) |
| Nausea | 31 (31) | 23 (23) | 4 (4) | 4 (4) |
| Cough | 30 (30) | 22 (22) | 8 (8) | 0 |
| Vomiting | 22 (22) | 17 (17) | 3 (3) | 2 (2) |
| Hypertension | 21 (21) | 4 (4) | 7 (7) | 10 (10) |
| Sinusitis | 21 (21) | 2 (2) | 17 (17) | 2 (2) |
| Fall | 19 (19) | 13 (13) | 5 (5) | 1 (1) |
| Fatigue | 19 (19) | 15 (15) | 3 (3) | 1 (1) |
| Back pain | 18 (18) | 9 (9) | 9 (9) | 0 |
| Nasal congestion | 18 (18) | 12 (12) | 6 (6) | 0 |
| Petechiae | 18 (18) | 17 (17) | 1 (1) | 0 |
| Rash | 17 (17) | 14 (14) | 3 (3) | 0 |
| Constipation | 16 (16) | 14 (14) | 2 (2) | 0 |
| Ecchymosis | 16 (16) | 15 (15) | 1 (1) | 0 |
| Gastroesophageal reflux disease | 16 (16) | 10 (10) | 6 (6) | 0 |
| Oropharyngeal pain | 16 (16) | 12 (12) | 4 (4) | 0 |
| Night sweats | 15 (15) | 11 (11) | 4 (4) | 0 |
| Peripheral edema | 15 (15) | 12 (12) | 3 (3) | 0 |
| . | All treated patients (N = 99) . | |||
|---|---|---|---|---|
| AE, n (%)* . | All grades . | Grade 1 . | Grade 2 . | Grade 3 . |
| Diarrhea | 51 (51) | 37 (37) | 9 (9) | 5 (5) |
| Headache | 45 (45) | 34 (34) | 6 (6) | 5 (5) |
| Upper respiratory tract infection | 44 (44) | 5 (5) | 38 (38) | 1 (1) |
| Arthralgia | 42 (42) | 29 (29) | 12 (12) | 1 (1) |
| Contusion | 42 (42) | 38 (38) | 4 (4) | 0 |
| Weight increased | 32 (32) | 15 (15) | 14 (14) | 3 (3) |
| Nausea | 31 (31) | 23 (23) | 4 (4) | 4 (4) |
| Cough | 30 (30) | 22 (22) | 8 (8) | 0 |
| Vomiting | 22 (22) | 17 (17) | 3 (3) | 2 (2) |
| Hypertension | 21 (21) | 4 (4) | 7 (7) | 10 (10) |
| Sinusitis | 21 (21) | 2 (2) | 17 (17) | 2 (2) |
| Fall | 19 (19) | 13 (13) | 5 (5) | 1 (1) |
| Fatigue | 19 (19) | 15 (15) | 3 (3) | 1 (1) |
| Back pain | 18 (18) | 9 (9) | 9 (9) | 0 |
| Nasal congestion | 18 (18) | 12 (12) | 6 (6) | 0 |
| Petechiae | 18 (18) | 17 (17) | 1 (1) | 0 |
| Rash | 17 (17) | 14 (14) | 3 (3) | 0 |
| Constipation | 16 (16) | 14 (14) | 2 (2) | 0 |
| Ecchymosis | 16 (16) | 15 (15) | 1 (1) | 0 |
| Gastroesophageal reflux disease | 16 (16) | 10 (10) | 6 (6) | 0 |
| Oropharyngeal pain | 16 (16) | 12 (12) | 4 (4) | 0 |
| Night sweats | 15 (15) | 11 (11) | 4 (4) | 0 |
| Peripheral edema | 15 (15) | 12 (12) | 3 (3) | 0 |
No grade 4 or 5 events reported.