Skin changes in patients receiving IMiD therapy
. | n (%) . |
---|---|
Total surveys | 106 |
No skin changes reported | 79 (74.5) |
Skin changes reported | 27 (25.5) |
Description of skin changes | 27 |
Pigmentation | |
Darkening (hyperpigmentation) | 22 (81.5) |
Lightening | 2 (7.4) |
Distribution | |
Spotty | 9 (33.3) |
Generalized | 2 (7.4) |
Other | 6 (22.2) |
Location of hyperpigmentation | 22 |
Palms/soles | 15 (68.2) |
Forearms | 7 (31.8) |
Face | 6 (27.2) |
Shins | 3 (13.6) |
Thighs | 3 (13.6) |
Chest | 3 (13.6) |
Everywhere | 3 (13.6) |
Other (back, abdomen, nails, fingers/toes, groin) | 5 (22.7) |
Time to onset of hyperpigmentation, mo | 22 |
<3 | 10 (45.5) |
3-6 | 4 (18.2) |
>6 | 6 (27.3) |
Unsure | 2 (9.1) |
Resolution of hyperpigmentation after IMiD discontinuation | 11 |
Not better | 2 (18.2) |
Partially better | 5 (45.5) |
Fully resolved | 4 (36.6) |
Score (1-10 scale) of distress caused by hyperpigmentation | 22 |
More bothersome (7-10 of 10) | 7 (31.8) |
Less bothersome (1-6 of 10) | 15 (68.2) |
Range | 1-9 |
. | n (%) . |
---|---|
Total surveys | 106 |
No skin changes reported | 79 (74.5) |
Skin changes reported | 27 (25.5) |
Description of skin changes | 27 |
Pigmentation | |
Darkening (hyperpigmentation) | 22 (81.5) |
Lightening | 2 (7.4) |
Distribution | |
Spotty | 9 (33.3) |
Generalized | 2 (7.4) |
Other | 6 (22.2) |
Location of hyperpigmentation | 22 |
Palms/soles | 15 (68.2) |
Forearms | 7 (31.8) |
Face | 6 (27.2) |
Shins | 3 (13.6) |
Thighs | 3 (13.6) |
Chest | 3 (13.6) |
Everywhere | 3 (13.6) |
Other (back, abdomen, nails, fingers/toes, groin) | 5 (22.7) |
Time to onset of hyperpigmentation, mo | 22 |
<3 | 10 (45.5) |
3-6 | 4 (18.2) |
>6 | 6 (27.3) |
Unsure | 2 (9.1) |
Resolution of hyperpigmentation after IMiD discontinuation | 11 |
Not better | 2 (18.2) |
Partially better | 5 (45.5) |
Fully resolved | 4 (36.6) |
Score (1-10 scale) of distress caused by hyperpigmentation | 22 |
More bothersome (7-10 of 10) | 7 (31.8) |
Less bothersome (1-6 of 10) | 15 (68.2) |
Range | 1-9 |