Table 8.

VTE, ATE, or mortality: univariate analysis

PredictorOR95% CIP*
Age >75 y 4.33 3.47-5.40 <.0001 
Female sex 0.97 0.78-1.21 .810 
Race    
 White 1.00 1.00-1.00  
 Black 0.73 0.55-0.96 .811 
 Asian 0.73 0.48-1.10 .843 
 Other 0.47 0.36-0.62 .0001 
Comorbidities    
 Hypertension 1.37 1.10-1.70 .005 
 Diabetes mellitus 1.30 1.03-1.65 .030 
 Coronary artery disease 2.45 1.78-3.39 <.0001 
 Congestive heart failure 1.99 1.31-3.00 .001 
 Atrial fibrillation 2.50 1.80-3.46 <.0001 
 Valvular heart disease 1.18 0.15-9.20 .872 
 Chronic renal disease 2.86 2.10-3.91 <.0001 
 Chronic lung disease 0.97 0.64-1.48 .897 
 Chronic liver disease 1.52 0.60-3.87 .378 
 Thyroid disease 1.58 1.10-2.26 .013 
 BMI >35 kg/m2 0.85 0.67-1.08 .186 
 ICU admission 2.66 2.10-3.38 <.0001 
 Bleeding history 2.39 1.78-3.21 <.0001 
 Ischemic stroke history 3.13 2.10-4.67 <.0001 
 Carotid occlusive disease history 3.23 2.19-4.77 <.0001 
 Peripheral arterial disease history 2.96 1.67-5.23 .0002 
VTE risk factors    
 Personal history of VTE 4.29 3.35-5.50 <.0001 
 Family history of VTE 4.07 2.30-7.20 <.0001 
 Thrombophilia 4.07 2.30-7.20 <.0001 
 Cancer history 1.57 1.18-2.08 .0019 
 Autoimmune disease 0.53 0.19-1.44 .211 
 Paraplegia/hemiplegia 1.63 0.37-7.12 .520 
IMPROVE-DD ≥4 3.64 2.91-4.55 <.0001 
D-dimer, ng/mL    
 0-920 (<4× ULN) 1.00 1.00-1.00  
 921-1380 (4-6× ULN) 1.51 0.99-2.30 .054 
 >1380 (>6× ULN) 1.81 1.43-2.31 <.0001 
NLR ≥3 1.39 1.07-1.81 .013 
Medications at discharge    
 Anticoagulants 0.85 0.60-1.21 .367 
 Antiplatelets 1.56 0.87-2.80 .137 
PredictorOR95% CIP*
Age >75 y 4.33 3.47-5.40 <.0001 
Female sex 0.97 0.78-1.21 .810 
Race    
 White 1.00 1.00-1.00  
 Black 0.73 0.55-0.96 .811 
 Asian 0.73 0.48-1.10 .843 
 Other 0.47 0.36-0.62 .0001 
Comorbidities    
 Hypertension 1.37 1.10-1.70 .005 
 Diabetes mellitus 1.30 1.03-1.65 .030 
 Coronary artery disease 2.45 1.78-3.39 <.0001 
 Congestive heart failure 1.99 1.31-3.00 .001 
 Atrial fibrillation 2.50 1.80-3.46 <.0001 
 Valvular heart disease 1.18 0.15-9.20 .872 
 Chronic renal disease 2.86 2.10-3.91 <.0001 
 Chronic lung disease 0.97 0.64-1.48 .897 
 Chronic liver disease 1.52 0.60-3.87 .378 
 Thyroid disease 1.58 1.10-2.26 .013 
 BMI >35 kg/m2 0.85 0.67-1.08 .186 
 ICU admission 2.66 2.10-3.38 <.0001 
 Bleeding history 2.39 1.78-3.21 <.0001 
 Ischemic stroke history 3.13 2.10-4.67 <.0001 
 Carotid occlusive disease history 3.23 2.19-4.77 <.0001 
 Peripheral arterial disease history 2.96 1.67-5.23 .0002 
VTE risk factors    
 Personal history of VTE 4.29 3.35-5.50 <.0001 
 Family history of VTE 4.07 2.30-7.20 <.0001 
 Thrombophilia 4.07 2.30-7.20 <.0001 
 Cancer history 1.57 1.18-2.08 .0019 
 Autoimmune disease 0.53 0.19-1.44 .211 
 Paraplegia/hemiplegia 1.63 0.37-7.12 .520 
IMPROVE-DD ≥4 3.64 2.91-4.55 <.0001 
D-dimer, ng/mL    
 0-920 (<4× ULN) 1.00 1.00-1.00  
 921-1380 (4-6× ULN) 1.51 0.99-2.30 .054 
 >1380 (>6× ULN) 1.81 1.43-2.31 <.0001 
NLR ≥3 1.39 1.07-1.81 .013 
Medications at discharge    
 Anticoagulants 0.85 0.60-1.21 .367 
 Antiplatelets 1.56 0.87-2.80 .137 

BMI, body mass index; NLR, neutrophil/lymphocyte ratio.

*

Bold font indicates significance.

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