MVA of survival outcomes in patients with t(8;21)
Covariate . | HR . | 95% CI . | P . |
---|---|---|---|
t(8;21) DFS | |||
Hypodiploidy vs pseudodiploidy | 0.414 | 0.210-0.815 | .011 |
Hyperdiploidy vs pseudodiploidy | 0.386 | 0.139-1.073 | .068 |
Deletion of 9q | 0.451 | 0.200-1.014 | .054 |
Presence of secondary chromosomal abnormalities | 1.053 | 0.541-2.050 | .879 |
t(8;21) OS | |||
Hypodiploidy vs pseudodiploidy | 0.482 | 0.216-1.074 | .074 |
Hyperdiploidy vs pseudodiploidy | 0.264 | 0.070-0.991 | .049 |
Deletion of 7q | 1.516 | 0.589-3.899 | .388 |
Deletion of 9q | 0.367 | 0.143-0.942 | .037 |
Presence of secondary chromosomal abnormalities | 0.943 | 0.410-2.143 | .888 |
Covariate . | HR . | 95% CI . | P . |
---|---|---|---|
t(8;21) DFS | |||
Hypodiploidy vs pseudodiploidy | 0.414 | 0.210-0.815 | .011 |
Hyperdiploidy vs pseudodiploidy | 0.386 | 0.139-1.073 | .068 |
Deletion of 9q | 0.451 | 0.200-1.014 | .054 |
Presence of secondary chromosomal abnormalities | 1.053 | 0.541-2.050 | .879 |
t(8;21) OS | |||
Hypodiploidy vs pseudodiploidy | 0.482 | 0.216-1.074 | .074 |
Hyperdiploidy vs pseudodiploidy | 0.264 | 0.070-0.991 | .049 |
Deletion of 7q | 1.516 | 0.589-3.899 | .388 |
Deletion of 9q | 0.367 | 0.143-0.942 | .037 |
Presence of secondary chromosomal abnormalities | 0.943 | 0.410-2.143 | .888 |
All MVAs were adjusted for age, WBC count at diagnosis, and KIT mutation (positive, negative, and not tested).