Table 3.

Multivariate analysis of EFS, PFS, and OS adjusted for strata

EFS HR (95% CI)PPFS HR (95% CI)POS HR (95% CI)P
Randomized patients       
 Allo-SCT vs auto-SCT 0.9 (0.6-1.5) .721 0.9 (0.5-1.5) .702 1.3 (0.7-2.4) .421 
 LDH > NORMAL 2.3 (1.3-4.1) .004 2.4 (1.4-4.4) .003 2.0 (1.0-4.3) .064 
 ECOG > 1 1.0 (0.5-1.8) .901 1.0 (0.5-1.8) .977 1.2 (0.6-2.5) .648 
 Stage III/IV 1.0 (0.4-2.2) .918 1.1 (0.5-2.6) .844 1.4 (0.4-4.8) .546 
 E > 1 1.2 (0.7-2.1) .492 1.2 (0.7-2.2) .429 1.0 (0.5-1.9) .896 
Transplant recipients       
 Allo-SCT vs auto-SCT* 0.8 (0.3-1.7) .513 0.8 (0.3-1.7) .513 1.8 (0.7-4.6) .218 
 LDH > NORMAL 1.4 (0.6-3.1) .455 1.4 (0.6-3.1) .455 1.0 (0.3-3.0) .977 
 ECOG > 1 1.1 (0.4-2.8) .886 1.1 (0.4-2.8) .886 2.3 (0.8-7.0) .140 
 Stage III/IV 1.3 (0.4-4.5) .645 1.3 (0.4-4.5) .645 1.2 (0.3-5.4) .807 
 E > 1 0.6 (0.2-1.7) .341 0.6 (0.2-1.7) .341 0.5 (0.1-1.8) .273 
EFS HR (95% CI)PPFS HR (95% CI)POS HR (95% CI)P
Randomized patients       
 Allo-SCT vs auto-SCT 0.9 (0.6-1.5) .721 0.9 (0.5-1.5) .702 1.3 (0.7-2.4) .421 
 LDH > NORMAL 2.3 (1.3-4.1) .004 2.4 (1.4-4.4) .003 2.0 (1.0-4.3) .064 
 ECOG > 1 1.0 (0.5-1.8) .901 1.0 (0.5-1.8) .977 1.2 (0.6-2.5) .648 
 Stage III/IV 1.0 (0.4-2.2) .918 1.1 (0.5-2.6) .844 1.4 (0.4-4.8) .546 
 E > 1 1.2 (0.7-2.1) .492 1.2 (0.7-2.2) .429 1.0 (0.5-1.9) .896 
Transplant recipients       
 Allo-SCT vs auto-SCT* 0.8 (0.3-1.7) .513 0.8 (0.3-1.7) .513 1.8 (0.7-4.6) .218 
 LDH > NORMAL 1.4 (0.6-3.1) .455 1.4 (0.6-3.1) .455 1.0 (0.3-3.0) .977 
 ECOG > 1 1.1 (0.4-2.8) .886 1.1 (0.4-2.8) .886 2.3 (0.8-7.0) .140 
 Stage III/IV 1.3 (0.4-4.5) .645 1.3 (0.4-4.5) .645 1.2 (0.3-5.4) .807 
 E > 1 0.6 (0.2-1.7) .341 0.6 (0.2-1.7) .341 0.5 (0.1-1.8) .273 
*

Seven patients randomized to allo-SCT are included.

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