Relationship of ABO-incompatible platelet transfusion on platelet recovery and poor neurological outcomes
Platelet recovery . | ABO incompatible . | ABO compatible . | Adjusted β (95% CI)* . | AOR (95% CI)† . | P . |
---|---|---|---|---|---|
ACI (platelets, ×103/μL),‡ median (IQR) | 2 (−19 to 28) | 15 (1-36) | −19.00 (−35.55 to −4.44) | — | .01 |
Neurologic outcome, n (%) | |||||
Discharge death | 16 (34.0) | 12 (15.4) | — | 2.59 (1.00-6.73) | .05 |
Discharge poor mRS (4-6) | 43 (91.5) | 60 (76.9) | — | 3.61 (0.97-13.42) | .06 |
3-mo poor mRS (4-6)§ | 30 (75.0) | 34 (69.4) | — | 1.47 (0.52-4.14) | .47 |
Platelet recovery . | ABO incompatible . | ABO compatible . | Adjusted β (95% CI)* . | AOR (95% CI)† . | P . |
---|---|---|---|---|---|
ACI (platelets, ×103/μL),‡ median (IQR) | 2 (−19 to 28) | 15 (1-36) | −19.00 (−35.55 to −4.44) | — | .01 |
Neurologic outcome, n (%) | |||||
Discharge death | 16 (34.0) | 12 (15.4) | — | 2.59 (1.00-6.73) | .05 |
Discharge poor mRS (4-6) | 43 (91.5) | 60 (76.9) | — | 3.61 (0.97-13.42) | .06 |
3-mo poor mRS (4-6)§ | 30 (75.0) | 34 (69.4) | — | 1.47 (0.52-4.14) | .47 |
Platelet recovery model adjusted for age of transfused platelets.
Neurologic outcome model adjusted for ICH score.
ACI scores were missing for 2.4% (n = 3); percentages are from 122 patients, 76 with compatible transfusions and 46 with incompatible transfusions.
Three-month loss to follow-up was 28.8% (n = 36); percentages are from 89 patients, 49 with compatible transfusions and 40 with incompatible transfusions.