Intergroup characteristic differences between ICH patients receiving ABO-incompatible and compatible platelet transfusions
| . | All patients (N = 125) . | ABO incompatible (n = 47) . | ABO compatible (n = 78) . |
|---|---|---|---|
| Age, mean (SD), y | 65 (15.4) | 64 (16.1) | 65 (15.1) |
| Male, n (%) | 72 (57.6) | 26 (55.3) | 46 (59.0) |
| Race, n (%) | |||
| White | 29 (23.2) | 9 (19.1) | 20 (25.6) |
| Black | 35 (28.0) | 16 (34.0) | 19 (24.4) |
| Hispanic | 51 (40.8) | 19 (40.4) | 32 (41.0) |
| Other/unknown | 10 (8.0) | 3 (6.4) | 7 (9.0) |
| Medical history, n (%) | |||
| Atrial fibrillation | 5 (4.0) | 1 (2.1) | 4 (5.1) |
| Coronary artery disease | 19 (15.2) | 7 (14.9) | 12 (15.4) |
| Dyslipidemia | 34 (27.2) | 11 (23.4) | 23 (29.5) |
| Hypertension | 97 (76.0) | 38 (80.9) | 57 (73.1) |
| Diabetes | 32 (25.6) | 10 (21.3) | 22 (28.2) |
| Clinical/radiographic | |||
| ICH score, median (IQR) | 2 (1-3) | 2 (1-3) | 1.5 (1-3) |
| ICH volume, median (IQR), mL | 13 (5-33) | 14 (3-41) | 12 (5-28) |
| Presence of IVH, n (%) | 66 (52.8) | 25 (53.2) | 41 (52.6) |
| ICH location, n (%) | |||
| Lobar | 36 (28.8) | 10 (21.3) | 26 (33.3) |
| Deep | 80 (64.0) | 35 (74.5) | 45 (57.7) |
| Infratentorial | 6 (4.8) | 2 (4.3) | 4 (5.1) |
| Brainstem | 3 (2.4) | 0 (0.0) | 3 (3.8) |
| Platelet age, median (IQR), d | 4 (4-5) | 4 (3-5) | 4 (4-5) |
| Time to transfusion, median (IQR), h | 3 (2-7) | 3 (2-7) | 4 (2-7) |
| Patient blood type, n (%) | |||
| O | 66 (52.8) | 41 (87.2) | 25 (32.1) |
| A | 42 (33.6) | 2 (4.3) | 40 (51.3) |
| B | 13 (10.4) | 4 (8.5) | 9 (11.5) |
| AB | 4 (3.2) | 0 (0.0) | 4 (5.1) |
| Mismatch type, n (%) | |||
| None | 63 (50.4) | N/A | 63 (80.8) |
| Major | 41 (32.8) | 41 (87.2) | N/A |
| Minor | 15 (12.0) | N/A | 15 (19.2) |
| Both | 6 (4.8) | 6 (12.8) | N/A |
| . | All patients (N = 125) . | ABO incompatible (n = 47) . | ABO compatible (n = 78) . |
|---|---|---|---|
| Age, mean (SD), y | 65 (15.4) | 64 (16.1) | 65 (15.1) |
| Male, n (%) | 72 (57.6) | 26 (55.3) | 46 (59.0) |
| Race, n (%) | |||
| White | 29 (23.2) | 9 (19.1) | 20 (25.6) |
| Black | 35 (28.0) | 16 (34.0) | 19 (24.4) |
| Hispanic | 51 (40.8) | 19 (40.4) | 32 (41.0) |
| Other/unknown | 10 (8.0) | 3 (6.4) | 7 (9.0) |
| Medical history, n (%) | |||
| Atrial fibrillation | 5 (4.0) | 1 (2.1) | 4 (5.1) |
| Coronary artery disease | 19 (15.2) | 7 (14.9) | 12 (15.4) |
| Dyslipidemia | 34 (27.2) | 11 (23.4) | 23 (29.5) |
| Hypertension | 97 (76.0) | 38 (80.9) | 57 (73.1) |
| Diabetes | 32 (25.6) | 10 (21.3) | 22 (28.2) |
| Clinical/radiographic | |||
| ICH score, median (IQR) | 2 (1-3) | 2 (1-3) | 1.5 (1-3) |
| ICH volume, median (IQR), mL | 13 (5-33) | 14 (3-41) | 12 (5-28) |
| Presence of IVH, n (%) | 66 (52.8) | 25 (53.2) | 41 (52.6) |
| ICH location, n (%) | |||
| Lobar | 36 (28.8) | 10 (21.3) | 26 (33.3) |
| Deep | 80 (64.0) | 35 (74.5) | 45 (57.7) |
| Infratentorial | 6 (4.8) | 2 (4.3) | 4 (5.1) |
| Brainstem | 3 (2.4) | 0 (0.0) | 3 (3.8) |
| Platelet age, median (IQR), d | 4 (4-5) | 4 (3-5) | 4 (4-5) |
| Time to transfusion, median (IQR), h | 3 (2-7) | 3 (2-7) | 4 (2-7) |
| Patient blood type, n (%) | |||
| O | 66 (52.8) | 41 (87.2) | 25 (32.1) |
| A | 42 (33.6) | 2 (4.3) | 40 (51.3) |
| B | 13 (10.4) | 4 (8.5) | 9 (11.5) |
| AB | 4 (3.2) | 0 (0.0) | 4 (5.1) |
| Mismatch type, n (%) | |||
| None | 63 (50.4) | N/A | 63 (80.8) |
| Major | 41 (32.8) | 41 (87.2) | N/A |
| Minor | 15 (12.0) | N/A | 15 (19.2) |
| Both | 6 (4.8) | 6 (12.8) | N/A |
IQR, interquartile range; IVH, intraventricular hemorrhage; N/A, not applicable; SD, standard deviation.