Clinical details of the patients with HLH and sepsis in this study
| Clinical details . | Values . |
|---|---|
| Patients, N | |
| HLH | 43 |
| Sepsis | 19 |
| Median age, y | |
| HLH (minimum, maximum) | 2.6 (0.2-25) |
| Sepsis (minimum, maximum) | 3.0 (0.2-17.5) |
| HLH diagnosis features, % | |
| Fever | 86 |
| Splenomegaly | 95 |
| Bicytopenia | 71 |
| Hyperferritinemia | 88 |
| Hypofibrinogenemia | 65 |
| Hypertriglyceridemia | 57 |
| Elevated sCD25 | 94 |
| HLH-associated genetic lesion, N | |
| Yes | 26 |
| No | 17 |
| HLH: infection, N | |
| EBV | 10 |
| Other viruses | 8 |
| Other infections | 2 |
| No infection | 23 |
| Sepsis: infection, N | |
| Gram-positive bacteria | 3 |
| Gram-negative bacteria | 8 |
| Virus | 1 |
| No identified organism | 7 |
| Outcome | |
| HLH: live/dead | 30/13 |
| Sepsis: live/dead | 19/0 |
| Clinical details . | Values . |
|---|---|
| Patients, N | |
| HLH | 43 |
| Sepsis | 19 |
| Median age, y | |
| HLH (minimum, maximum) | 2.6 (0.2-25) |
| Sepsis (minimum, maximum) | 3.0 (0.2-17.5) |
| HLH diagnosis features, % | |
| Fever | 86 |
| Splenomegaly | 95 |
| Bicytopenia | 71 |
| Hyperferritinemia | 88 |
| Hypofibrinogenemia | 65 |
| Hypertriglyceridemia | 57 |
| Elevated sCD25 | 94 |
| HLH-associated genetic lesion, N | |
| Yes | 26 |
| No | 17 |
| HLH: infection, N | |
| EBV | 10 |
| Other viruses | 8 |
| Other infections | 2 |
| No infection | 23 |
| Sepsis: infection, N | |
| Gram-positive bacteria | 3 |
| Gram-negative bacteria | 8 |
| Virus | 1 |
| No identified organism | 7 |
| Outcome | |
| HLH: live/dead | 30/13 |
| Sepsis: live/dead | 19/0 |