Table 4.

Multiple Cox model of time to relapse in the subcohort

ParameterRelapse-specific HR95% CIP
TruncatedorAEA− vs nontruncatedandAEA+ 1.69 1.05-2.74 .03 
Age at diagnosis ≥10 y vs <10 y 2.44 1.48-4.01 <.001 
CNS status at diagnosis    
 CNS 2 vs CNS 1 0.69 0.25-1.92 .48 
 CNS 3 vs CNS 1 1.16 0.41-3.27 .78 
MRD group, day 29    
 MRD 3 vs MRD 4 1.05 0.42-2.61 .92 
 MRD 2 vs MRD 4 1.43 0.76-2.69 .27 
 MRD 1 vs MRD 4 2.85 1.58-5.15 .001 
Doubling in WBC at diagnosis 1.15 1.02-1.29 .02 
ParameterRelapse-specific HR95% CIP
TruncatedorAEA− vs nontruncatedandAEA+ 1.69 1.05-2.74 .03 
Age at diagnosis ≥10 y vs <10 y 2.44 1.48-4.01 <.001 
CNS status at diagnosis    
 CNS 2 vs CNS 1 0.69 0.25-1.92 .48 
 CNS 3 vs CNS 1 1.16 0.41-3.27 .78 
MRD group, day 29    
 MRD 3 vs MRD 4 1.05 0.42-2.61 .92 
 MRD 2 vs MRD 4 1.43 0.76-2.69 .27 
 MRD 1 vs MRD 4 2.85 1.58-5.15 .001 
Doubling in WBC at diagnosis 1.15 1.02-1.29 .02 
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