Table 1. The characteristics of the... | American Society of Hematology

Table 1.

The characteristics of the patients

Case	Sex	Age, y	Infected cell	Clonality of the infected cells	Clinical findings	EBV-DNA load of each fraction of PBMCs, copies/μg DNA					Pathological diagnosis	The rate of the EBV-infected cell fractions in PBMCs, %
Case	Sex	Age, y	Infected cell	Clonality of the infected cells	Clinical findings	Total PBMCs	CD4⁺ cells	CD8⁺ cells	CD56⁺ cells	Others	Pathological diagnosis	The rate of the EBV-infected cell fractions in PBMCs, %
CD4-1	F	25	CD4	Monoclonal	Fever, HMB	7.0 × 10⁴	2.2 × 10⁵	ND	ND	ND	CAEBV	71.2
CD4-2	F	62	CD4	Monoclonal	Fever, LD	3.2 × 10⁴	4.6 × 10⁵	ND	ND	ND	ND*	23.5
CD4-3	M	33	CD4	Monoclonal	Fever	9.2 × 10³	1.0 × 10⁵	ND	ND	ND	CAEBV	54.2
CD8-1	F	21	CD8	Monoclonal	Fever, LD	1.8 × 10³	ND	6.0 × 10²	ND	ND	CAEBV	50.0
CD8-2	F	64	CD8	Monoclonal	Fever, LD	2.6 × 10⁵	ND	1.2 × 10⁶	ND	ND	CAEBV	51.0
CD8-3	F	64	CD8	Monoclonal	Fever, LD	4.7 × 10⁴	ND	1.7 × 10⁴	ND	ND	CAEBV	51.1
CD56-1	F	18	CD56	Monoclonal	Fever, HMB	5.2 × 10⁴	ND	ND	1.1 × 10⁶	ND	CAEBV	3.8
CD56-2	F	48	CD56	Monoclonal	Fever, LD	8.6 × 10⁴	ND	ND	1.0 × 10⁵	ND	ND*	10.0
CD56-3	M	23	CD56	Monoclonal	Fever, colitis	2.9 × 10³	ND	ND	2.1 × 10⁴	ND	ND*	4.2
CD4/56-1	F	18	CD4/56	Monoclonal	Fever, LD	6.0 × 10⁴	1.7 × 10⁶	ND	7.1 × 10⁶	ND	CAEBV	35.2 (CD4), 2.3 (CD56)

Case	Sex	Age, y	Infected cell	Clonality of the infected cells	Clinical findings	EBV-DNA load of each fraction of PBMCs, copies/μg DNA					Pathological diagnosis	The rate of the EBV-infected cell fractions in PBMCs, %
Case	Sex	Age, y	Infected cell	Clonality of the infected cells	Clinical findings	Total PBMCs	CD4⁺ cells	CD8⁺ cells	CD56⁺ cells	Others	Pathological diagnosis	The rate of the EBV-infected cell fractions in PBMCs, %
CD4-1	F	25	CD4	Monoclonal	Fever, HMB	7.0 × 10⁴	2.2 × 10⁵	ND	ND	ND	CAEBV	71.2
CD4-2	F	62	CD4	Monoclonal	Fever, LD	3.2 × 10⁴	4.6 × 10⁵	ND	ND	ND	ND*	23.5
CD4-3	M	33	CD4	Monoclonal	Fever	9.2 × 10³	1.0 × 10⁵	ND	ND	ND	CAEBV	54.2
CD8-1	F	21	CD8	Monoclonal	Fever, LD	1.8 × 10³	ND	6.0 × 10²	ND	ND	CAEBV	50.0
CD8-2	F	64	CD8	Monoclonal	Fever, LD	2.6 × 10⁵	ND	1.2 × 10⁶	ND	ND	CAEBV	51.0
CD8-3	F	64	CD8	Monoclonal	Fever, LD	4.7 × 10⁴	ND	1.7 × 10⁴	ND	ND	CAEBV	51.1
CD56-1	F	18	CD56	Monoclonal	Fever, HMB	5.2 × 10⁴	ND	ND	1.1 × 10⁶	ND	CAEBV	3.8
CD56-2	F	48	CD56	Monoclonal	Fever, LD	8.6 × 10⁴	ND	ND	1.0 × 10⁵	ND	ND*	10.0
CD56-3	M	23	CD56	Monoclonal	Fever, colitis	2.9 × 10³	ND	ND	2.1 × 10⁴	ND	ND*	4.2
CD4/56-1	F	18	CD4/56	Monoclonal	Fever, LD	6.0 × 10⁴	1.7 × 10⁶	ND	7.1 × 10⁶	ND	CAEBV	35.2 (CD4), 2.3 (CD56)

F, female; HMB, hypersensitivity to mosquito bites; LD, liver dysfunction; M, male; ND, not detected.

The diagnosis of CAEBV was made by clinical findings and detecting EBV-infected T or NK cells using unfixed PB as shown in “Materials and methods.”