Table 4. Summary of grade 3, 4, and 5... | American Society of Hematology

Table 4.

Summary of grade 3, 4, and 5 AEs

AE	Azacitidine arm*		Observation arm
AE	Any grade (no. of events), n = 302	Grade 3-5 (no. of events)†	Any grade (no. of events, n = 215	Grade 3-5 (no. of events)
Hematologic	143	58	5	5
Thrombocytopenia	119	29	1	1
Poor graft function	33	29	2	2
Nonhematologic	159	33	210	56
Infection	42	13	52	19
Gastrointestinal	41	0	44	12
Hepatic	17	9	19	5
Pulmonary	7	4	8	6
Skin	27	2	32	5

AE	Azacitidine arm*		Observation arm
AE	Any grade (no. of events), n = 302	Grade 3-5 (no. of events)†	Any grade (no. of events, n = 215	Grade 3-5 (no. of events)
Hematologic	143	58	5	5
Thrombocytopenia	119	29	1	1
Poor graft function	33	29	2	2
Nonhematologic	159	33	210	56
Infection	42	13	52	19
Gastrointestinal	41	0	44	12
Hepatic	17	9	19	5
Pulmonary	7	4	8	6
Skin	27	2	32	5

There were 325 any grade AEs in the azacitidine arm, but 302 were related to the azacitidine intervention.

†

There was no grade 5 hematologic toxicity in the azacitidine arm. There was only one grade 5 toxicity, which was pulmonary and associated with aspiration pneumonia.

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