Table 1. Causes of screen failures... | American Society of Hematology

Table 1.

Causes of screen failures (February 2011 through April 2017), N = 561

Cause	n/N	%
Failed eligibility criteria	233/561	41
Multiple comorbidity	135/233
Thrombocytopenia	32/233
Neutropenia	3/233
Pancytopenia	15/233
Relapsed or graft failure	29/233
Secondary malignancy	5/233
Other	14/233
Patient was not interested	129/561	23
Physician was not interested (some received AZA off-study)	84/561	15
Detectable minimal residual disease after transplant (received AZA off-study)	26/561	5
No clinical trial benefit	28/561	5
Outside physician refused	10/561	2
On competing IND study	10/561	2

Cause	n/N	%
Failed eligibility criteria	233/561	41
Multiple comorbidity	135/233
Thrombocytopenia	32/233
Neutropenia	3/233
Pancytopenia	15/233
Relapsed or graft failure	29/233
Secondary malignancy	5/233
Other	14/233
Patient was not interested	129/561	23
Physician was not interested (some received AZA off-study)	84/561	15
Detectable minimal residual disease after transplant (received AZA off-study)	26/561	5
No clinical trial benefit	28/561	5
Outside physician refused	10/561	2
On competing IND study	10/561	2

AZA, azacitidine; IND, investigational new drug.