OS based on stage migration
| . | Modified Mayo 2004 stage . | Mayo 2012 stage . | ||
|---|---|---|---|---|
| OS (years) if stage changed from: . | Same vs worsened . | Same vs improved . | Same vs worsened . | Same vs improved . |
| Baseline to 3 mo | 10.5 vs 4.0; P < .001 | 10.5 vs 10.8; P = .27 | 9.8 vs 4.0; P = .01 | 9.8 vs 10.5; P = .21 |
| Baseline to 6 mo | 8.1 vs 5.1; P = .004 | 8.1 vs NR; P = .08 | NR vs 3.8; P < .001 | NR vs 8.1; P = .47 |
| Baseline to 3 mo restricting to > stage 2 patients | Not assessed | 3.5 vs 10.8; P < .001 | Not assessed | 2.6 vs 8.1; P < .001 |
| Baseline to 6 mo restricting to > stage 2 patients | Not assessed | 5.0 vs NR; P = .02 | Not assessed | 3.7 vs 5.9; P = .12 |
| . | Modified Mayo 2004 stage . | Mayo 2012 stage . | ||
|---|---|---|---|---|
| OS (years) if stage changed from: . | Same vs worsened . | Same vs improved . | Same vs worsened . | Same vs improved . |
| Baseline to 3 mo | 10.5 vs 4.0; P < .001 | 10.5 vs 10.8; P = .27 | 9.8 vs 4.0; P = .01 | 9.8 vs 10.5; P = .21 |
| Baseline to 6 mo | 8.1 vs 5.1; P = .004 | 8.1 vs NR; P = .08 | NR vs 3.8; P < .001 | NR vs 8.1; P = .47 |
| Baseline to 3 mo restricting to > stage 2 patients | Not assessed | 3.5 vs 10.8; P < .001 | Not assessed | 2.6 vs 8.1; P < .001 |
| Baseline to 6 mo restricting to > stage 2 patients | Not assessed | 5.0 vs NR; P = .02 | Not assessed | 3.7 vs 5.9; P = .12 |
The impact of improving, worsening, or retaining original stage at 3 and 6 mo in the entire cohort, and in patients who had advanced stage at diagnosis.