Clinical characteristics at diagnosis of patients with AL amyloidosis included in the study (N = 1357)
| Parameter at diagnosis . | Median (interquartile range) or n (%) . |
|---|---|
| Age, y | 64 (58-71) |
| Sex (male) | 888 (65) |
| Cardiac involvement | 760 (74) |
| Renal involvement | 599 (58) |
| Liver involvement | 167 (16) |
| >1 organ involvement | 618 (60) |
| NT-ProBNP, ng/L | 2442 (501-6669) |
| Troponin T, µg/L | 0.03 (0.01-0.08) |
| dFLC, mg/dL | 19.7 (7.5-53.2) |
| Creatinine, mg/dL | 1.1 (0.9-1.6) |
| Alkaline phosphatase, IU/L | 99 (74-151) |
| Serum albumin, g/dL | 2.8 (2.2-3.2) |
| Serum beta2microglobulin, µg/mL | 3.4 (2.5-5.2) |
| Urine protein, g/24 h | 1.2 (0.2-5.0) |
| Bone marrow plasma cells, % | 10 (5-18) |
| Parameter at diagnosis . | Median (interquartile range) or n (%) . |
|---|---|
| Age, y | 64 (58-71) |
| Sex (male) | 888 (65) |
| Cardiac involvement | 760 (74) |
| Renal involvement | 599 (58) |
| Liver involvement | 167 (16) |
| >1 organ involvement | 618 (60) |
| NT-ProBNP, ng/L | 2442 (501-6669) |
| Troponin T, µg/L | 0.03 (0.01-0.08) |
| dFLC, mg/dL | 19.7 (7.5-53.2) |
| Creatinine, mg/dL | 1.1 (0.9-1.6) |
| Alkaline phosphatase, IU/L | 99 (74-151) |
| Serum albumin, g/dL | 2.8 (2.2-3.2) |
| Serum beta2microglobulin, µg/mL | 3.4 (2.5-5.2) |
| Urine protein, g/24 h | 1.2 (0.2-5.0) |
| Bone marrow plasma cells, % | 10 (5-18) |