Table 1.

Clinical and radiological characteristics of 206 cancer-associated SSPE cases

CharacteristicCategoriesN (%)
Sex Female 87 (42.2) 
ECOG performance status 46 (22.7) 
 94 (46.3) 
 33 (16.3) 
 25 (12.3) 
 5 (2.5) 
Cancer type*   
 Lung 39 (18.9) 
 Colorectal 18 (8.7) 
 Breast 18 (8.7) 
 Hematologic 17 (8.3) 
 Urologic 17 (8.3) 
 Gynecologic 15 (7.3) 
 Sarcoma 15 (7.3) 
 Esophageal 11 (5.3) 
 Pancreatic 9 (4.4) 
 Gastric 6 (2.9) 
 Other 41 (19.9) 
AJCC stage 9 (4.7) 
 14 (7.4) 
 28 (14.7) 
 139 (73.2) 
Cancer status Active disease 17 7(85.9) 
 Remission within 2 y 17 (8.3) 
 >2 y since remission 12 (5.8) 
Central nervous tumor or metastasis  21 (10.2) 
Lung or pleural metastasis  101 (49) 
Liver metastasis  43 (20.9) 
Active chemotherapy  108 (53.2) 
Endocrine therapy  11 (5.4) 
Antiangiogenic therapy  21 (10.3) 
Major surgery within 30 d before SSPE  25 (12.) 
History of venous thrombosis  23 (11.2) 
Other indication for long-term anticoagulation  30 (14.6) 
Concurrent antiplatelet therapy  35 (17) 
Obesity  68 (33) 
Concurrent use of erythropoietin agents  1 (0.5) 
Type of CT study CT chest PE protocol 68 (33) 
 Contrast-enhanced CT 138 (67) 
Single SSPE  139 (70.9) 
Right pulmonary artery location  132 (64.1) 
RV/LV ratio >1  11 (5.3) 
CharacteristicCategoriesN (%)
Sex Female 87 (42.2) 
ECOG performance status 46 (22.7) 
 94 (46.3) 
 33 (16.3) 
 25 (12.3) 
 5 (2.5) 
Cancer type*   
 Lung 39 (18.9) 
 Colorectal 18 (8.7) 
 Breast 18 (8.7) 
 Hematologic 17 (8.3) 
 Urologic 17 (8.3) 
 Gynecologic 15 (7.3) 
 Sarcoma 15 (7.3) 
 Esophageal 11 (5.3) 
 Pancreatic 9 (4.4) 
 Gastric 6 (2.9) 
 Other 41 (19.9) 
AJCC stage 9 (4.7) 
 14 (7.4) 
 28 (14.7) 
 139 (73.2) 
Cancer status Active disease 17 7(85.9) 
 Remission within 2 y 17 (8.3) 
 >2 y since remission 12 (5.8) 
Central nervous tumor or metastasis  21 (10.2) 
Lung or pleural metastasis  101 (49) 
Liver metastasis  43 (20.9) 
Active chemotherapy  108 (53.2) 
Endocrine therapy  11 (5.4) 
Antiangiogenic therapy  21 (10.3) 
Major surgery within 30 d before SSPE  25 (12.) 
History of venous thrombosis  23 (11.2) 
Other indication for long-term anticoagulation  30 (14.6) 
Concurrent antiplatelet therapy  35 (17) 
Obesity  68 (33) 
Concurrent use of erythropoietin agents  1 (0.5) 
Type of CT study CT chest PE protocol 68 (33) 
 Contrast-enhanced CT 138 (67) 
Single SSPE  139 (70.9) 
Right pulmonary artery location  132 (64.1) 
RV/LV ratio >1  11 (5.3) 

AJCC, American Joint Committee on Cancer; ECOG, Eastern Cooperative Oncology Group; RV/LV, right ventricular/left ventricular; SSPE, subsegmental pulmonary embolism.

*

Patients had multiple concurrent malignancies.

Calculated based on the number of patients (N = 190) classified using AJCC system, when available and applicable.

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