Patient and donor characteristics for 3 transfusions preceding detection of unexplained Rh antibody specificities in individuals with thalassemia
| UPID . | Specificity . | RH haplotypes (presumed) . | Patient Rh phenotype . | Patient race . | Donor unit phenotypes . | No. units from Black donors . | |
|---|---|---|---|---|---|---|---|
| T7 | anti-D | RHD-Ce | DeletedD-ce | D+ C+ c+ E− e+ | Middle Eastern | 6D+, 2 D− | 5 of 8 |
| T12 | anti-C | RHD-Ce | RHD-CE | D+ C+ c− E+ e+ | White | 6C+, 0C− | 5 of 6 |
| anti-D | 6D+, 0D− | 5 of 6 | |||||
| T23 | anti-C | RHD-Ce | RHD-cE | D+ C+ c+ E+ e+ | Asian | 0C+, 6C− | 5 of 6 |
| T25 | anti-D | RHD-Ce | RHD-cE | D+ C+ c+ E+ e+ | Asian | 4D+, 2D− | 2 of 6 |
| T29* | anti-D | RHD-ce | RHD-ce(48C) | D+ C− c+ E− e+ | White | 5D+, 2D− | 3 of 7 |
| T30 | anti-E† | RHD-Ce | RHD-Ce | D+ C+ c− E− e+ | White | 0E+, 3E− | 3 of 3 |
| T34 | anti-E† | RHD-Ce | RHD-Ce | D+ C+ c− E− e+ | Indian | 0E+, 7E− | 4 of 7 |
| anti-C | 0C+, 6C− | 5 of 6 | |||||
| anti-e | 7e+, 0e− | 6 of 7 | |||||
| T52 | anti-C† | DeletedD-ce | DeletedD-ce | D− C− c+ E− e+ | Middle Eastern | 0C+, 3C− | 0 of 3 |
| anti-D† | 0D+, 5D− | 1 of 5 | |||||
| UPID . | Specificity . | RH haplotypes (presumed) . | Patient Rh phenotype . | Patient race . | Donor unit phenotypes . | No. units from Black donors . | |
|---|---|---|---|---|---|---|---|
| T7 | anti-D | RHD-Ce | DeletedD-ce | D+ C+ c+ E− e+ | Middle Eastern | 6D+, 2 D− | 5 of 8 |
| T12 | anti-C | RHD-Ce | RHD-CE | D+ C+ c− E+ e+ | White | 6C+, 0C− | 5 of 6 |
| anti-D | 6D+, 0D− | 5 of 6 | |||||
| T23 | anti-C | RHD-Ce | RHD-cE | D+ C+ c+ E+ e+ | Asian | 0C+, 6C− | 5 of 6 |
| T25 | anti-D | RHD-Ce | RHD-cE | D+ C+ c+ E+ e+ | Asian | 4D+, 2D− | 2 of 6 |
| T29* | anti-D | RHD-ce | RHD-ce(48C) | D+ C− c+ E− e+ | White | 5D+, 2D− | 3 of 7 |
| T30 | anti-E† | RHD-Ce | RHD-Ce | D+ C+ c− E− e+ | White | 0E+, 3E− | 3 of 3 |
| T34 | anti-E† | RHD-Ce | RHD-Ce | D+ C+ c− E− e+ | Indian | 0E+, 7E− | 4 of 7 |
| anti-C | 0C+, 6C− | 5 of 6 | |||||
| anti-e | 7e+, 0e− | 6 of 7 | |||||
| T52 | anti-C† | DeletedD-ce | DeletedD-ce | D− C− c+ E− e+ | Middle Eastern | 0C+, 3C− | 0 of 3 |
| anti-D† | 0D+, 5D− | 1 of 5 | |||||
Patient Rh antigen phenotype was predicted by RHD and RHCE genotype.
T29 also received transfusions at an outside hospital that were CEK-matched while at college before anti-D.
†Denotes Rh specificities identified in antigen-negative patients who received antigen negative units. Antibodies listed in order of identification for patients with multiple specificities: UPID T12 anti-C 5/2012, -D 2/2015; T34 anti-E 5/2017, -11C/2017, -e 3/2018; T52 anti-C 4/2011, -D 2/2015, and also had anti-Jsa 7/2011, -Kpa 12/2015.