Table 3.

Patient and donor characteristics for 3 transfusions preceding detection of unexplained Rh antibody specificities in individuals with thalassemia

UPIDSpecificityRH haplotypes (presumed)Patient Rh phenotypePatient raceDonor unit phenotypesNo. units from Black donors
T7 anti-D RHD-Ce DeletedD-ce D+ C+ c+ E− e+ Middle Eastern 6D+, 2 D− 5 of 8 
T12 anti-C RHD-Ce RHD-CE D+ C+ c− E+ e+ White 6C+, 0C− 5 of 6 
 anti-D     6D+, 0D− 5 of 6 
T23 anti-C RHD-Ce RHD-cE D+ C+ c+ E+ e+ Asian 0C+, 6C− 5 of 6 
T25 anti-D RHD-Ce RHD-cE D+ C+ c+ E+ e+ Asian 4D+, 2D− 2 of 6 
T29* anti-D RHD-ce RHD-ce(48C) D+ C− c+ E− e+ White 5D+, 2D− 3 of 7 
T30 anti-E RHD-Ce RHD-Ce D+ C+ c− E− e+ White 0E+, 3E− 3 of 3 
T34 anti-E RHD-Ce RHD-Ce D+ C+ c− E− e+ Indian 0E+, 7E− 4 of 7 
 anti-C     0C+, 6C− 5 of 6 
 anti-e     7e+, 0e− 6 of 7 
T52 anti-C DeletedD-ce DeletedD-ce D− C− c+ E− e+ Middle Eastern 0C+, 3C− 0 of 3 
 anti-D     0D+, 5D− 1 of 5 
UPIDSpecificityRH haplotypes (presumed)Patient Rh phenotypePatient raceDonor unit phenotypesNo. units from Black donors
T7 anti-D RHD-Ce DeletedD-ce D+ C+ c+ E− e+ Middle Eastern 6D+, 2 D− 5 of 8 
T12 anti-C RHD-Ce RHD-CE D+ C+ c− E+ e+ White 6C+, 0C− 5 of 6 
 anti-D     6D+, 0D− 5 of 6 
T23 anti-C RHD-Ce RHD-cE D+ C+ c+ E+ e+ Asian 0C+, 6C− 5 of 6 
T25 anti-D RHD-Ce RHD-cE D+ C+ c+ E+ e+ Asian 4D+, 2D− 2 of 6 
T29* anti-D RHD-ce RHD-ce(48C) D+ C− c+ E− e+ White 5D+, 2D− 3 of 7 
T30 anti-E RHD-Ce RHD-Ce D+ C+ c− E− e+ White 0E+, 3E− 3 of 3 
T34 anti-E RHD-Ce RHD-Ce D+ C+ c− E− e+ Indian 0E+, 7E− 4 of 7 
 anti-C     0C+, 6C− 5 of 6 
 anti-e     7e+, 0e− 6 of 7 
T52 anti-C DeletedD-ce DeletedD-ce D− C− c+ E− e+ Middle Eastern 0C+, 3C− 0 of 3 
 anti-D     0D+, 5D− 1 of 5 

Patient Rh antigen phenotype was predicted by RHD and RHCE genotype.

*

T29 also received transfusions at an outside hospital that were CEK-matched while at college before anti-D.

†Denotes Rh specificities identified in antigen-negative patients who received antigen negative units. Antibodies listed in order of identification for patients with multiple specificities: UPID T12 anti-C 5/2012, -D 2/2015; T34 anti-E 5/2017, -11C/2017, -e 3/2018; T52 anti-C 4/2011, -D 2/2015, and also had anti-Jsa 7/2011, -Kpa 12/2015.