Effect of clinical variables on GI biopsy subcrypt RARαhi cell numbers
| Variable . | No. of patients . | Mean subcrypt RARαhi cell no. ± SE . | P* . |
|---|---|---|---|
| Recipient age | |||
| Below median | 25 | 1387 ± 248 | .957 |
| Above median | 25 | 1407 ± 280 | |
| Recipient diagnosis | |||
| Lymphoid malignancy | 30 | 1404 ± 244 | .910 |
| Myeloid malignancy | 20 | 1387 ± 289 | |
| Donor | |||
| Family | 19 | 1182 ± 361 | .420 |
| Unrelated | 31 | 1522 ± 204 | |
| Conditioning | |||
| RIC | 46 | 1422 ± 198 | .450 |
| FIC | 4 | 1112 ± 426 | |
| HLA match in GVHD vector | |||
| Fully matched | 46 | 1231 ± 169 | .09 |
| Single antigen mismatch | 4 | 3263 ± 818 | |
| T-cell depletion | |||
| No | 44 | 1276 ± 175 | .286 |
| Yes | 6 | 2002 ± 817 | |
| Time to biopsy | |||
| Before day +180 | 31 | 1574 ± 246 | .219 |
| After day +180 | 19 | 1117 ± 272 | |
| Histologic GVHD | |||
| No | 10 | 498 ± 85 | <.001 |
| Yes | 40 | 1599 ± 213 |
| Variable . | No. of patients . | Mean subcrypt RARαhi cell no. ± SE . | P* . |
|---|---|---|---|
| Recipient age | |||
| Below median | 25 | 1387 ± 248 | .957 |
| Above median | 25 | 1407 ± 280 | |
| Recipient diagnosis | |||
| Lymphoid malignancy | 30 | 1404 ± 244 | .910 |
| Myeloid malignancy | 20 | 1387 ± 289 | |
| Donor | |||
| Family | 19 | 1182 ± 361 | .420 |
| Unrelated | 31 | 1522 ± 204 | |
| Conditioning | |||
| RIC | 46 | 1422 ± 198 | .450 |
| FIC | 4 | 1112 ± 426 | |
| HLA match in GVHD vector | |||
| Fully matched | 46 | 1231 ± 169 | .09 |
| Single antigen mismatch | 4 | 3263 ± 818 | |
| T-cell depletion | |||
| No | 44 | 1276 ± 175 | .286 |
| Yes | 6 | 2002 ± 817 | |
| Time to biopsy | |||
| Before day +180 | 31 | 1574 ± 246 | .219 |
| After day +180 | 19 | 1117 ± 272 | |
| Histologic GVHD | |||
| No | 10 | 498 ± 85 | <.001 |
| Yes | 40 | 1599 ± 213 |
FIC, full-intensity conditioning; RIC, reduced-intensity conditioning; SE, standard error.
Unpaired Student t test without assuming equal variance.