Multivariate analysis of prespecified parameters for OS and PFS
| Covariate . | Group . | OS . | PFS . | ||
|---|---|---|---|---|---|
| P . | HR (95% CI) . | P . | HR (95% CI) . | ||
| Disease stage | I-II | 1.00 | 1.00 | ||
| III-IV | .58 | 0.491 (0.23-1.02) | .205 | 0.63 (0.32-1.28) | |
| B symptoms | No | 1.00 | 1.00 | ||
| Yes | .008 | 2.01 (1.01-3.93) | .023 | 1.58 (0.81-3.08) | |
| CRP | <ULN | 1.00 | 1.00 | ||
| >ULN | .24 | 1.31 (0.63-2.76) | .09 | 1.35 (0.65-2.81) | |
| LDH | <ULN | 1.00 | 1.00 | ||
| >ULN | .001 | 3.77 (1.61-8.77) | .001 | 2.36 (1.01-5.36) | |
| ECOG-PS | ≥2 | 1.00 | 1.00 | ||
| ≤2 | .001 | 4.04 (2.07-7.84) | .001 | 3.69 (1.67-7.50) | |
| Covariate . | Group . | OS . | PFS . | ||
|---|---|---|---|---|---|
| P . | HR (95% CI) . | P . | HR (95% CI) . | ||
| Disease stage | I-II | 1.00 | 1.00 | ||
| III-IV | .58 | 0.491 (0.23-1.02) | .205 | 0.63 (0.32-1.28) | |
| B symptoms | No | 1.00 | 1.00 | ||
| Yes | .008 | 2.01 (1.01-3.93) | .023 | 1.58 (0.81-3.08) | |
| CRP | <ULN | 1.00 | 1.00 | ||
| >ULN | .24 | 1.31 (0.63-2.76) | .09 | 1.35 (0.65-2.81) | |
| LDH | <ULN | 1.00 | 1.00 | ||
| >ULN | .001 | 3.77 (1.61-8.77) | .001 | 2.36 (1.01-5.36) | |
| ECOG-PS | ≥2 | 1.00 | 1.00 | ||
| ≤2 | .001 | 4.04 (2.07-7.84) | .001 | 3.69 (1.67-7.50) | |