Table 6. Bleeding events in patients... | American Society of Hematology

Table 6.

Bleeding events in patients with grade 3 or 4 CRS, with and without fibrinogen replacement therapy

	Fibrinogen replacement therapy
	Yes, n = 23	No, n = 34
Lowest fibrinogen, n	23	33*
Lowest fibrinogen, median (range), g/L	1.15 (0.40-3.71)	3.12 (0.83-6.75)
Bleeding event, n (%)†	n = 23	n = 34
No bleeding	10 (43)	21 (62)
Any grade	13 (57)	13 (38)
Grade 1	1 (4)	6 (18)
Grade 2	6 (26)	3 (9)
Grade 3	4 (17)	4 (18)
Grade 4	2 (9)	0

	Fibrinogen replacement therapy
	Yes, n = 23	No, n = 34
Lowest fibrinogen, n	23	33*
Lowest fibrinogen, median (range), g/L	1.15 (0.40-3.71)	3.12 (0.83-6.75)
Bleeding event, n (%)†	n = 23	n = 34
No bleeding	10 (43)	21 (62)
Any grade	13 (57)	13 (38)
Grade 1	1 (4)	6 (18)
Grade 2	6 (26)	3 (9)
Grade 3	4 (17)	4 (18)
Grade 4	2 (9)	0

Bleeding event grade corresponds to maximum grade.

One patient did not have a documented fibrinogen level.

Number of patients with an event.