Multivariable analysis of neighborhood poverty exposure and transplantation outcomes
| Outcome . | HR (95%CI)* . | P . |
|---|---|---|
| Malignant disease cohort | ||
| All-cause mortality (n = 2037) | 1.04 (0.88-1.23) | .620 |
| TRM (n = 1981) | 1.34 (1.02-1.76) | .037 |
| Relapse (n = 1996) | 0.97 (0.74-1.26) | .808 |
| Acute GVHD grade 2-4 (n = 2042) | 1.01 (0.82-1.25) | .905 |
| Chronic GVHD (n = 2030) | 1.01 (0.77-1.32) | .966 |
| Infection through day 100 (n = 1401) | 1.09 (0.94-1.28) | .250 |
| Nonmalignant disease cohort | ||
| All-cause mortality (n = 1696) | 1.20 (0.95-1.52) | .126 |
| Acute GVHD grade 2-4 (n = 1692) | 0.86 (0.62-1.18) | .348 |
| Chronic GVHD (n = 1660) | 1.24 (0.96-1.6) | .102 |
| Infection through day 100 (n = 1274) | 0.89 (0.74-1.08) | .230 |
| Outcome . | HR (95%CI)* . | P . |
|---|---|---|
| Malignant disease cohort | ||
| All-cause mortality (n = 2037) | 1.04 (0.88-1.23) | .620 |
| TRM (n = 1981) | 1.34 (1.02-1.76) | .037 |
| Relapse (n = 1996) | 0.97 (0.74-1.26) | .808 |
| Acute GVHD grade 2-4 (n = 2042) | 1.01 (0.82-1.25) | .905 |
| Chronic GVHD (n = 2030) | 1.01 (0.77-1.32) | .966 |
| Infection through day 100 (n = 1401) | 1.09 (0.94-1.28) | .250 |
| Nonmalignant disease cohort | ||
| All-cause mortality (n = 1696) | 1.20 (0.95-1.52) | .126 |
| Acute GVHD grade 2-4 (n = 1692) | 0.86 (0.62-1.18) | .348 |
| Chronic GVHD (n = 1660) | 1.24 (0.96-1.6) | .102 |
| Infection through day 100 (n = 1274) | 0.89 (0.74-1.08) | .230 |
High vs low poverty. Neighborhood poverty defined by linkage of a child’s residential ZIP code at the time of HCT to US Census3 and categorized as high-poverty neighborhood (≥20% of persons living below 100% FPL) or low-poverty neighborhood (<20% of persons below 100% FPL).1-4