Factors to consider when assessing patients with suspected thromboembolism recurrence on standard-intensity warfarin/VKA
| 1. Confirmation by appropriate imaging of new thrombosis or thrombosis extension |
| 2. Review of the INR results before the thrombosis for assessment of patient adherence |
| 3. Check that the patient’s INR assessment has been performed by using an LA-insensitive thromboplastin |
| 4. Test for heparin-induced thrombocytopenia45 if rethrombosis occurs within 14 d of starting LMWH |
| 5. Consideration of provoking factors (eg, immobility, surgery) for VTE or additional risk factors for thrombosis (eg, malignancy, SLE or other autoimmune disease, myeloproliferative neoplasm) |
| 6. Consideration of bleeding risk factors (eg, gastrointestinal or uterine, thrombocytopenia), as such factors may limit anticoagulation intensity |
| 1. Confirmation by appropriate imaging of new thrombosis or thrombosis extension |
| 2. Review of the INR results before the thrombosis for assessment of patient adherence |
| 3. Check that the patient’s INR assessment has been performed by using an LA-insensitive thromboplastin |
| 4. Test for heparin-induced thrombocytopenia45 if rethrombosis occurs within 14 d of starting LMWH |
| 5. Consideration of provoking factors (eg, immobility, surgery) for VTE or additional risk factors for thrombosis (eg, malignancy, SLE or other autoimmune disease, myeloproliferative neoplasm) |
| 6. Consideration of bleeding risk factors (eg, gastrointestinal or uterine, thrombocytopenia), as such factors may limit anticoagulation intensity |