Table 4.

Response to emicizumab

Response to emicizumabMedianIQRRange
Bleeding stopped, d 3-4 2-15* 
Day last rhFVIIa injection 1.5 0.8-4 0-16* 
FVIII (chromogenic), d    
 >5% (human) 3.3-4.8 1-13 
 >10% (human) 11 7.5-12 5-13 
 >50% (human) 105 33-184 9-270 
 >5% (bovine) 60 26-73 12-201 
 >10% (bovine) 85 33-112 12-270 
 >50% (bovine) 115 67-185 18-403 
Response to emicizumabMedianIQRRange
Bleeding stopped, d 3-4 2-15* 
Day last rhFVIIa injection 1.5 0.8-4 0-16* 
FVIII (chromogenic), d    
 >5% (human) 3.3-4.8 1-13 
 >10% (human) 11 7.5-12 5-13 
 >50% (human) 105 33-184 9-270 
 >5% (bovine) 60 26-73 12-201 
 >10% (bovine) 85 33-112 12-270 
 >50% (bovine) 115 67-185 18-403 

Medians, IQR, range; n = 12.

*

One patient with an abdominal wound requiring repetitive single doses of rhFVIIa for surgical procedures.

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