Table 2.

Clinical and laboratory features for considering the diagnosis of CTP

Features to consider when diagnosing CTP
Inexplicable platelet count in relation to treatment 
Thrombocytosis during TPO-RA treatment 
Mild or no bleeding despite severe thrombocytopenia 
Fluctuations of white cells and reticulocytes 
Inverse fluctuation of TPO and platelet counts 
Periodic megakaryocytic hypoplasia or aplasia 
Fluctuations in synchrony with menstrual cycle 
T-cell receptor rearrangement 
Blood diseases or disorders of the thyroid gland 
Features to consider when diagnosing CTP
Inexplicable platelet count in relation to treatment 
Thrombocytosis during TPO-RA treatment 
Mild or no bleeding despite severe thrombocytopenia 
Fluctuations of white cells and reticulocytes 
Inverse fluctuation of TPO and platelet counts 
Periodic megakaryocytic hypoplasia or aplasia 
Fluctuations in synchrony with menstrual cycle 
T-cell receptor rearrangement 
Blood diseases or disorders of the thyroid gland 

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