Pathogenesis of CTP
| . | Patients, n . | References . |
|---|---|---|
| (Auto)immune-mediated platelet destruction | 16 | 2-15 |
| Megakaryocytic hypoplasia | 15 | 4, 9, 11, 12, 14, 16-21 |
| T-cell receptor rearrangement | 7 | 14, 15, 22 |
| Abnormal regulation of platelet production | 12 | 10, 19, 21, 23-30 |
| Menstrual cycle synchronized | 10 | 2, 3, 7, 15, 19, 31-33 |
| Associated with other disorders | ||
| Disorders of the thyroid gland | 10 | 2, 15, 27 |
| Hematological malignancies | 22 | 14, 15, 21, 25, 26, 34 |
| Cyclic neutropenia | 1 | 35 |
| . | Patients, n . | References . |
|---|---|---|
| (Auto)immune-mediated platelet destruction | 16 | 2-15 |
| Megakaryocytic hypoplasia | 15 | 4, 9, 11, 12, 14, 16-21 |
| T-cell receptor rearrangement | 7 | 14, 15, 22 |
| Abnormal regulation of platelet production | 12 | 10, 19, 21, 23-30 |
| Menstrual cycle synchronized | 10 | 2, 3, 7, 15, 19, 31-33 |
| Associated with other disorders | ||
| Disorders of the thyroid gland | 10 | 2, 15, 27 |
| Hematological malignancies | 22 | 14, 15, 21, 25, 26, 34 |
| Cyclic neutropenia | 1 | 35 |
Proposed pathomechanisms are heterogeneous and not necessarily mutually exclusive.