Distribution of baseline characteristics according to quartiles of plasma levels of VWF
| . | Plasma VWF, % . | |||
|---|---|---|---|---|
| Quartile 1 (<88.5) . | Quartile 2 (88.5-94.6) . | Quartile 3 (94.7-104.7) . | Quartile 4 (≥104.7) . | |
| n | 298 | 305 | 315 | 339 |
| Age, y | 56.4 ± 14.1 | 58.9 ± 14.1 | 61.3 ± 12.8 | 63.9 ± 13.0 |
| Males | 49.7 (148) | 47.9 (146) | 46.7 (147) | 44.5 (151) |
| BMI, kg/m2 | 25.5 ± 3.8 | 26.8 ± 4.5 | 26.1 ± 3.7 | 27.0 ± 4.8 |
| CRP, mg/L | 1.29 (0.65-2.35) | 1.05 (0.59-1.90) | 1.14 (0.65-1.88) | 1.36 (0.72-2.36) |
| Hypertension* | 49.8 (148) | 55.6 (169) | 54.9 (173) | 62.2 (211) |
| Cancer† | 4.8 (12) | 6.2 (15) | 8.1 (20) | 4.3 (11) |
| CVD† | 10.1 (30) | 17.4 (53) | 18.7 (59) | 16.8 (57) |
| Estrogen use‡ | 4.4 (13) | 4.3 (13) | 5.7 (18) | 4.7 (16) |
| Smoking‡ | 45.3 (135) | 28.2 (86) | 23.5 (74) | 26.3 (89) |
| . | Plasma VWF, % . | |||
|---|---|---|---|---|
| Quartile 1 (<88.5) . | Quartile 2 (88.5-94.6) . | Quartile 3 (94.7-104.7) . | Quartile 4 (≥104.7) . | |
| n | 298 | 305 | 315 | 339 |
| Age, y | 56.4 ± 14.1 | 58.9 ± 14.1 | 61.3 ± 12.8 | 63.9 ± 13.0 |
| Males | 49.7 (148) | 47.9 (146) | 46.7 (147) | 44.5 (151) |
| BMI, kg/m2 | 25.5 ± 3.8 | 26.8 ± 4.5 | 26.1 ± 3.7 | 27.0 ± 4.8 |
| CRP, mg/L | 1.29 (0.65-2.35) | 1.05 (0.59-1.90) | 1.14 (0.65-1.88) | 1.36 (0.72-2.36) |
| Hypertension* | 49.8 (148) | 55.6 (169) | 54.9 (173) | 62.2 (211) |
| Cancer† | 4.8 (12) | 6.2 (15) | 8.1 (20) | 4.3 (11) |
| CVD† | 10.1 (30) | 17.4 (53) | 18.7 (59) | 16.8 (57) |
| Estrogen use‡ | 4.4 (13) | 4.3 (13) | 5.7 (18) | 4.7 (16) |
| Smoking‡ | 45.3 (135) | 28.2 (86) | 23.5 (74) | 26.3 (89) |
Continuous variables are shown as mean (± standard deviation) or median (25th-75th percentile). Categorical variables are shown as percentages (n).
Defined as systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg.
Self-reported history of cancer or myocardial infarction, angina, or stroke (CVD) at baseline.
Self-reported daily use of oral contraceptives or hormonal replacement therapy (estrogen use) or smoking of cigarettes or cigars (smoking).