Table 1.

Provisional classification of patients in the low-risk group (at diagnosis)

FeatureType/value/definition
Lineage B-precursor ALL 
Age, y 1.0 to 9.9 
Leukocyte count, ×109/L <50 
CNS involvement CNS 1 or 2 
Testicular involvement No 
DNA index >0.95 
Genotype Excluded: t(9;22)/BCR-ABL, t(1;19)/TCF3-PBX1, t(17;19)/TCF3/HLF, KMT2A rearrangement, and iAMP21 
FeatureType/value/definition
Lineage B-precursor ALL 
Age, y 1.0 to 9.9 
Leukocyte count, ×109/L <50 
CNS involvement CNS 1 or 2 
Testicular involvement No 
DNA index >0.95 
Genotype Excluded: t(9;22)/BCR-ABL, t(1;19)/TCF3-PBX1, t(17;19)/TCF3/HLF, KMT2A rearrangement, and iAMP21 
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