2016 WHO classification of mature, aggressive TCLs
PTCL-NOS |
Nodal lymphomas of TFH-cell origin, including AITL |
ALCL, ALK+ and ALK− |
ATLL: acute and lymphomatous |
Extranodal T-NK-cell lymphoma, nasal type |
Intestinal TCL: EATL and monomorphic epitheliotropic intestinal TCL |
Hepatosplenic TCL |
Primary cutaneous CD8+ aggressive epidermotropic cytotoxic TCL |
Breast implant–associated ALCL: extended disease beyond the capsule (stages II- IV) |
PTCL-NOS |
Nodal lymphomas of TFH-cell origin, including AITL |
ALCL, ALK+ and ALK− |
ATLL: acute and lymphomatous |
Extranodal T-NK-cell lymphoma, nasal type |
Intestinal TCL: EATL and monomorphic epitheliotropic intestinal TCL |
Hepatosplenic TCL |
Primary cutaneous CD8+ aggressive epidermotropic cytotoxic TCL |
Breast implant–associated ALCL: extended disease beyond the capsule (stages II- IV) |
ATLL, adult T-cell leukemia/lymphoma; EATL, enteropathy-associated TCL; MEITL, monomorphic epitheliotropic intestinal TCL.