Characteristics of total patient cohort with subgroups for patients who developed venous thrombosis, arterial thrombosis, or bleeding within 90 days of index admission
| . | Total, no. (%) . | Venous thrombosis . | Arterial thrombosis . | Bleeding . | |||||
|---|---|---|---|---|---|---|---|---|---|
| No. (%) . | P . | No. (%) . | P . | No. (%) . | P . | ||||
| No. of patients | 303 | 22 (7.2) | 6 (2.0) | 15 (5.0) | |||||
| Median age (IQR), y | 73 (57-82) | 58 (54-65) | .002 | 78 (77-80) | .484 | 80 (72-82) | .059 | ||
| Male sex | 165 (54.3) | 15 (68.2) | .192 | 2 (33.3) | .417 | 7 (53) | 1 | ||
| Median BMI (IQR) | 27 (24-32) | 29 (25-33) | .195 | 23 (20-25) | .023 | 29 (24-33) | .836 | ||
| No comorbidity | 50 (16.5) | 6 (27.3) | .226 | 1 (16.7) | 1 | 2 (13) | 1 | ||
| Hypertension | 133 (43.8) | 6 (27.3) | .121 | 2 (33.3) | .698 | 6 (40) | .796 | ||
| Diabetes | 85 (27.9) | 5 (22.7) | .806 | 1 (16.7) | 1 | 1 (7) | .076 | ||
| IHD or PVD | 54 (17.8) | 1 (4.5) | .143 | 2 (33.3) | .291 | 3 (20) | .736 | ||
| TIA or stroke | 31 (10.2) | 0 | .145 | 0 | 1 | 3 (20) | .189 | ||
| Prior VTE | 19 (6.3) | 1 (4.5) | 1 | 0 | 1 | 2 (13) | .24 | ||
| COPD or asthma | 83 (27.3) | 7 (31.8) | .625 | 2 (33.3) | .667 | 4 (27) | 1 | ||
| Malignancy | 47 (15.5) | 3 (13.6) | 1 | 0 | .595 | 4 (27) | .264 | ||
| CKD | 68 (22.4) | 3 (13.6) | .428 | 2 (33.3) | .619 | 3 (20) | 1 | ||
| Preadmission antiplatelet | 62 (20.4) | 4 (18.2) | 1 | 1 (16.7) | 1 | 2 (13) | .744 | ||
| Preadmission anticoagulant | 58 (19.1) | 0 | .011 | 1 (16.7) | 1 | 6 (40) | .046 | ||
| Ward | 236 (77.6) | 6 (27.3) | <.001 | 4 (66.7) | .617 | 14 (93) | .204 | ||
| ICU or HDU | 67 (22) | 16 (72.7) | 2 (33.3) | 1 (7) | |||||
| Oxygen | 237 (77) | 6 (27.3) | <.001 | 4 (66.7) | .777 | 14 (93) | .448 | ||
| NIV | 36 (11.8) | 3 (13.6) | 1 (16.7) | 0 | |||||
| Intubated | 30 (9.9) | 13 (59.1) | 1 (16.7) | 1 (7) | |||||
| Proned | 24 (7.9) | 9 (40.9) | <.001 | 0 | 1 | 1 (7) | 1 | ||
| Cardiovascular support | 17 (5.6) | 6 (27.3) | .001 | 1 (16.7) | .295 | 0 | |||
| Renal replacement | 12 (4) | 7 (31.8) | <.001 | 1 (16.7) | .217 | 1 (7) | .414 | ||
| Length of stay in ICU, d | 9 (7-14) | 15 (9-23) | <.001 | 78 | 8 | ||||
| Length of stay in the hospital, d | 7 (7-9) | 21 (12-32) | <.001 | 7.5 (5-30) | .518 | 12 (7-23) | .02 | ||
| . | Total, no. (%) . | Venous thrombosis . | Arterial thrombosis . | Bleeding . | |||||
|---|---|---|---|---|---|---|---|---|---|
| No. (%) . | P . | No. (%) . | P . | No. (%) . | P . | ||||
| No. of patients | 303 | 22 (7.2) | 6 (2.0) | 15 (5.0) | |||||
| Median age (IQR), y | 73 (57-82) | 58 (54-65) | .002 | 78 (77-80) | .484 | 80 (72-82) | .059 | ||
| Male sex | 165 (54.3) | 15 (68.2) | .192 | 2 (33.3) | .417 | 7 (53) | 1 | ||
| Median BMI (IQR) | 27 (24-32) | 29 (25-33) | .195 | 23 (20-25) | .023 | 29 (24-33) | .836 | ||
| No comorbidity | 50 (16.5) | 6 (27.3) | .226 | 1 (16.7) | 1 | 2 (13) | 1 | ||
| Hypertension | 133 (43.8) | 6 (27.3) | .121 | 2 (33.3) | .698 | 6 (40) | .796 | ||
| Diabetes | 85 (27.9) | 5 (22.7) | .806 | 1 (16.7) | 1 | 1 (7) | .076 | ||
| IHD or PVD | 54 (17.8) | 1 (4.5) | .143 | 2 (33.3) | .291 | 3 (20) | .736 | ||
| TIA or stroke | 31 (10.2) | 0 | .145 | 0 | 1 | 3 (20) | .189 | ||
| Prior VTE | 19 (6.3) | 1 (4.5) | 1 | 0 | 1 | 2 (13) | .24 | ||
| COPD or asthma | 83 (27.3) | 7 (31.8) | .625 | 2 (33.3) | .667 | 4 (27) | 1 | ||
| Malignancy | 47 (15.5) | 3 (13.6) | 1 | 0 | .595 | 4 (27) | .264 | ||
| CKD | 68 (22.4) | 3 (13.6) | .428 | 2 (33.3) | .619 | 3 (20) | 1 | ||
| Preadmission antiplatelet | 62 (20.4) | 4 (18.2) | 1 | 1 (16.7) | 1 | 2 (13) | .744 | ||
| Preadmission anticoagulant | 58 (19.1) | 0 | .011 | 1 (16.7) | 1 | 6 (40) | .046 | ||
| Ward | 236 (77.6) | 6 (27.3) | <.001 | 4 (66.7) | .617 | 14 (93) | .204 | ||
| ICU or HDU | 67 (22) | 16 (72.7) | 2 (33.3) | 1 (7) | |||||
| Oxygen | 237 (77) | 6 (27.3) | <.001 | 4 (66.7) | .777 | 14 (93) | .448 | ||
| NIV | 36 (11.8) | 3 (13.6) | 1 (16.7) | 0 | |||||
| Intubated | 30 (9.9) | 13 (59.1) | 1 (16.7) | 1 (7) | |||||
| Proned | 24 (7.9) | 9 (40.9) | <.001 | 0 | 1 | 1 (7) | 1 | ||
| Cardiovascular support | 17 (5.6) | 6 (27.3) | .001 | 1 (16.7) | .295 | 0 | |||
| Renal replacement | 12 (4) | 7 (31.8) | <.001 | 1 (16.7) | .217 | 1 (7) | .414 | ||
| Length of stay in ICU, d | 9 (7-14) | 15 (9-23) | <.001 | 78 | 8 | ||||
| Length of stay in the hospital, d | 7 (7-9) | 21 (12-32) | <.001 | 7.5 (5-30) | .518 | 12 (7-23) | .02 | ||
Data are presented as number of patients affected (% of patients within subgroup) for categorical variables, and as median (IQR) for continuous variables. P values represent the result of either Fisher’s exact test for categorical variables or Mann-Whitney U test for continuous variables comparing patients who had the event with those who did not have the event. P < .05 is bolded.
BMI, body mass index; NIV, noninvasive ventilation (high-flow nasal oxygen, continuous positive airway pressure ventilation, bilevel positive airway pressure ventilation); TIA, transient ischemic attack.