Patient characteristics in the matched-pairs analysis of patients who underwent transplantation in the 1990s or from 2013 through 2016
| Variable . | . | 1990s . | 2013-2016 . |
|---|---|---|---|
| Donor cell source | |||
| Bone marrow | 2746 (73.9) | 512 (13.8) | |
| Peripheral blood | 972 (26.1) | 3206 (86.2) | |
| Diagnosis | |||
| Acute lymphoblastic leukemia | 930 (25) | ||
| Acute myeloid leukemia | 1838 (49.4) | ||
| Lymphoma | 486 (13.1) | ||
| Myelodysplastic/myeloproliferative disease | 464 (12.5) | ||
| Complete remission at transplantation | |||
| Yes | 2538 (68.3) | ||
| No | 1180 (31.7) | ||
| Patient age, y | |||
| 18-24 | 571 (15.4) | ||
| 25-29 | 421 (11.3) | ||
| 30-34 | 446 (12) | ||
| 35-39 | 507 (13.6) | ||
| 40-44 | 615 (16.5) | ||
| 45-49 | 593 (15.9) | ||
| 50-54 | 374 (10.1) | ||
| 55-59 | 147 (4) | ||
| 60-64 | 41 (1.1) | ||
| 65-69 | 1 (0) | ||
| 70-75 | 2 (0.1) | ||
| Patient sex | |||
| Male | 2134 (57.4) | ||
| Female | 1584 (42.6) | ||
| Donor sex | |||
| Male | 2065 (55.5) | 2050 (55.1) | |
| Female | 1653 (44.5) | 1668 (44.9) | |
| Intensity of conditioning | |||
| Reduced | 286 (7.7) | 1009 (27.1) | |
| Myeloablative | 3432 (92.3) | 2709 (72.9) | |
| Conditioning contains total body irradiation | |||
| Yes | 2641 (71) | 1043 (28.1) | |
| No | 1077 (29) | 2675 (71.9) | |
| In vivo T-cell depletion | |||
| Yes | 322 (8.7) | 1214 (32.7) | |
| No | 3396 (91.3) | 2504 (67.3) | |
| Median follow-up, mo (95% CI) | 210.0 (204.4-216.3) | 28.3 (27.2-29.7) | |
| Variable . | . | 1990s . | 2013-2016 . |
|---|---|---|---|
| Donor cell source | |||
| Bone marrow | 2746 (73.9) | 512 (13.8) | |
| Peripheral blood | 972 (26.1) | 3206 (86.2) | |
| Diagnosis | |||
| Acute lymphoblastic leukemia | 930 (25) | ||
| Acute myeloid leukemia | 1838 (49.4) | ||
| Lymphoma | 486 (13.1) | ||
| Myelodysplastic/myeloproliferative disease | 464 (12.5) | ||
| Complete remission at transplantation | |||
| Yes | 2538 (68.3) | ||
| No | 1180 (31.7) | ||
| Patient age, y | |||
| 18-24 | 571 (15.4) | ||
| 25-29 | 421 (11.3) | ||
| 30-34 | 446 (12) | ||
| 35-39 | 507 (13.6) | ||
| 40-44 | 615 (16.5) | ||
| 45-49 | 593 (15.9) | ||
| 50-54 | 374 (10.1) | ||
| 55-59 | 147 (4) | ||
| 60-64 | 41 (1.1) | ||
| 65-69 | 1 (0) | ||
| 70-75 | 2 (0.1) | ||
| Patient sex | |||
| Male | 2134 (57.4) | ||
| Female | 1584 (42.6) | ||
| Donor sex | |||
| Male | 2065 (55.5) | 2050 (55.1) | |
| Female | 1653 (44.5) | 1668 (44.9) | |
| Intensity of conditioning | |||
| Reduced | 286 (7.7) | 1009 (27.1) | |
| Myeloablative | 3432 (92.3) | 2709 (72.9) | |
| Conditioning contains total body irradiation | |||
| Yes | 2641 (71) | 1043 (28.1) | |
| No | 1077 (29) | 2675 (71.9) | |
| In vivo T-cell depletion | |||
| Yes | 322 (8.7) | 1214 (32.7) | |
| No | 3396 (91.3) | 2504 (67.3) | |
| Median follow-up, mo (95% CI) | 210.0 (204.4-216.3) | 28.3 (27.2-29.7) | |
Data are absolute number (percentage) of patients, unless noted otherwise.