Table 2.

Frequency of CH in adults with HLH

CohortAll (%)<60 y (%)>60 y (%)
Adult HLH 26 22 36 
Acuna-Hidalgo et al11  
Abelson et al12  11 14 
CohortAll (%)<60 y (%)>60 y (%)
Adult HLH 26 22 36 
Acuna-Hidalgo et al11  
Abelson et al12  11 14 

Frequency of CH with a VAF >0.02 identified in the HLH cohort and healthy adults from published cohorts, determined by targeted sequencing of 71 genes11  or 111 genes.12 

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