Table 1. RCTs comparing prophylactic... | American Society of Hematology

Table 1.

RCTs comparing prophylactic platelet-transfusion thresholds

Study/Year	10 × 10³/µL threshold		20 × 10³/µL threshold		P
Study/Year	No. of patients	Major bleeding	No. of patients	Major bleeding	P
Rebulla et al⁵/1997	135	22%	120	20%	.41
Heckman et al⁶/1997	37	4 episodes/patient	41	2 episodes/patient	.12
Zumberg et al⁷/2002	78	14%	81	17%	.66
Diedrich et al⁸/2005*	79	18%	87	14%	NS

Study/Year	10 × 10³/µL threshold		20 × 10³/µL threshold		P
Study/Year	No. of patients	Major bleeding	No. of patients	Major bleeding	P
Rebulla et al⁵/1997	135	22%	120	20%	.41
Heckman et al⁶/1997	37	4 episodes/patient	41	2 episodes/patient	.12
Zumberg et al⁷/2002	78	14%	81	17%	.66
Diedrich et al⁸/2005*	79	18%	87	14%	NS

NS, not significant.

Compared 10 × 10³/µL vs 30 × 10³/µL.